(Q73721666)

English

Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed

scientific article published on 01 May 2000

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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1 reference

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author name string

G J Peters

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

B van Triest

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

H H Backus

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

C M Kuiper

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

C L van der Wilt

5

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Europe PubMed Central

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6 November 2019

H M Pinedo

6

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Europe PubMed Central

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6 November 2019

publication date

1 May 2000

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

European Journal of Cancer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

36

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6 November 2019

7

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Europe PubMed Central

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6 November 2019

916-924

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Clinical relevance of biochemical modulation of 5-fluorouracil

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Open, randomized, multicenter trial of raltitrexed versus fluorouracil plus high-dose leucovorin in patients with advanced colorectal cancer. Tomudex Colorectal Cancer Study Group.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

‘Tomudex’ (ZD1694): Results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. Tomudex Colorectal Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

P53, cell cycle control and apoptosis: Implications for cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulators of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 and WAF1 are induced and Rb protein is hypophosphorylated during cell growth inhibition by the thymidylate synthase inhibitor ZD1694 (Tomudex)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of an RNA binding site for human thymidylate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of thymidylate synthase as an RNA binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of mouse thymidylate synthase promoter activity by the wild-type p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of metabolism and cytotoxicity of cytosine arabinoside with N-(phosphon)-acetyl-L-aspartate in human leukemic blast cells and cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

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Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

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Transformation of mouse fibroblasts with the oncogenes H-ras OR trk is associated with pronounced changes in drug sensitivity and metabolism

1 reference

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7 January 2021

based on heuristic

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Cell cycle disturbances and apoptosis induced by topotecan and gemcitabine on human lung cancer cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Screening the p53 status of human cell lines using a yeast functional assay

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical and pathological associations with p53 tumour-suppressor gene mutations and expression of p21WAF1/Cip1 in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900026-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0959-8049(00)00026-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10785598%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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