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Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization
scientific article published on 01 May 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author name string
M A Lohrum
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
M Ashcroft
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
M H Kubbutat
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
K H Vousden
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
language of work or name
English
0 references
publication date
1 May 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Current Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
10
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
539-542
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
cites work
Regulation of p53 stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation and activation of p53 and its family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor surveillance via the ARF-p53 pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleolar Arf sequesters Mdm2 and activates p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a cryptic nucleolar-localization signal in MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900472-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0960-9822(00)00472-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed publication ID
10801444
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10801444
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801444%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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