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Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions
scientific article published on 01 January 1997
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
main subject
drug interaction
0 references
author name string
C L Crespi
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
B W Penman
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
publication date
1 January 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Advances in Pharmacology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
43
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
171-188
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
cites work
Human cytochrome P450IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1.
1 reference
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Crossref
reference URL
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7 January 2021
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A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing
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7 January 2021
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The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin B1 and comparison to CYP1A2 and CYP2A3.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
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A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human cell lines, derived from AHH-1 TK+/- human lymphoblasts, genetically engineered for expression of cytochromes P450.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
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inferred from DOI database lookup
Comparison of substrate metabolism by wild type CYP2D6 protein and a variant containing methionine, not valine, at position 374.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
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Enzymatic basis of the debrisoquine/sparteine-type genetic polymorphism of drug oxidation. Characterization of bufuralol 1'-hydroxylation in liver microsomes of in vivo phenotyped carriers of the genetic deficiency
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
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inferred from DOI database lookup
Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
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inferred from DOI database lookup
Cyclosporine dose reduction by ketoconazole administration in renal transplant recipients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochromes P450 expression systems
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome P450TB (CYP2C): a major monooxygenase catalyzing diclofenac 4'-hydroxylation in human liver
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
based on heuristic
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Polymorphic hydroxylation of Debrisoquine in man.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
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P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
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Analysis of human lymphoblast mutation assays by using historical negative control data bases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a human cell line expressing high levels of cDNA-derived CYP2D6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of a human lymphoblastoid cell line constitutively expressing human CYP1A1 cDNA: substrate specificity with model substrates and promutagens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960205-7
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7 January 2021
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Optimization of yeast-expressed human liver cytochrome P450 3A4 catalytic activities by coexpressing NADPH-cytochrome P450 reductase and cytochrome b5.
1 reference
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Crossref
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Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily
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Influence of ionic strength on the P450 monooxygenase reaction and role of cytochrome b5 in the process
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Clinical importance of hepatic cytochrome P450 in drug metabolism
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A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus
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Heterologous expression of cytochrome P-450 in Escherichia coli
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Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man
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Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme
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Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s
1 reference
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Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation
1 reference
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1 reference
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7 January 2021
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Identifiers
DOI
10.1016/S1054-3589(08)60205-7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed publication ID
9342176
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9342176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9342176%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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