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p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53
scientific article published on 01 April 2001
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
main subject
Burkitt lymphoma
1 reference
based on heuristic
inferred from title
homozygosity
1 reference
based on heuristic
inferred from title
author
Mikael S. Lindström
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Klas Wiman
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
U Klangby
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 April 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
20
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
2171-2177
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
17
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1204303
0 references
cites work
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p53 in MDM2-overexpressing cells through phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Concurrent disruption of p16INK4a and the ARF-p53 pathway predicts poor prognosis in aggressive non-Hodgkin's lymphoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intraclonal molecular heterogeneity suggests a hierarchy of pathogenetic events in Burkitt's lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multistep evolution of B-cell-derived tumors in humans and rodents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Twist is a potential oncogene that inhibits apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of a gene encoding a p53-associated protein in human sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
INK4a/ARF locus alterations in human non-Hodgkin's lymphomas mainly occur in tumors with wild-type p53 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The INK4A/ARF locus and its two gene products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ARF/p53 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biological activities of p53 mutants in Burkitt's lymphoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleolar Arf sequesters Mdm2 and activates p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204303
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1204303
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Dimensions Publication ID
1031787605
0 references
PubMed ID
11360201
1 reference
stated in
Europe PubMed Central
PubMed ID
11360201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360201%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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