(Q73898225)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia (English)

1 reference

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7 November 2019

1 reference

7

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7 November 2019

author name string

M J O'Neill

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

L Bogaert

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

C A Hicks

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

A Bond

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

M A Ward

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

G Ebinger

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Y Michotte

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

D Lodge

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

publication date

1 July 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

1575-1588

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

Brain cooling during transient focal ischemia provides complete neuroprotection

7 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The effects of ifenprodil and eliprodil on voltage-dependent Ca2+ channels and in gerbil global cerebral ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

SB 201823-A, a neuronal Ca2+ antagonist is neuroprotective in two models of cerebral ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

L-type voltage-dependent calcium channels do not modulate aminergic neurotransmitter release induced by transient global cerebral ischaemia: an in vivo microdialysis study in rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Neuropharmacology of AMPA and kainate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

AMPA receptor antagonists and local cerebral glucose utilization in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Lesioning the substantia nigra reduces striatal infarct volume following focal ischemia in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Focal cerebral ischemia in the cat: pretreatment with a competitive NMDA receptor antagonist, D-CPP-ene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Neuroprotective effect of the AMPA receptor antagonist LY-293558 in focal cerebral ischemia in the cat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Regulation of glutamate release by presynaptic kainate receptors in the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Kainate receptors: subunits, synaptic localization and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Dopamine depletion protects striatal neurons from ischemia-induced cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Delayed and prolonged post-ischemic hypothermia is neuroprotective in the gerbil.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

MK-801 reduced cerebral ischemic injury by inducing hypothermia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Trends and future developments in the pharmacological treatment of acute ischaemic stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The neuroprotective effects of the decahydroisoquinoline, LY 215490; a novel AMPA antagonist in focal ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Pharmacology of AMPA antagonists and their role in neuroprotection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischaemia model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Mitochondria and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Combined postischemic hypothermia and delayed MK-801 treatment attenuates neurobehavioral deficits associated with transient global ischemia in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Brain temperature and the neuroprotective action of enadoline and dizocilpine in the gerbil model of global ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Evaluation of glycine site antagonists of the NMDA receptor in global cerebral ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Protection against post-ischemic behavioral pathology by the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX) in the gerbil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

A novel AMPA receptor antagonist, YM872, reduces infarct size after middle cerebral artery occlusion in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Calcium in ischemic cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Cerestat and other NMDA antagonists in ischemic stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Stereoselective effects-of 2,3-benzodiazepines in vivo: electrophysiology and neuroprotection studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Excitatory amino acid neurotoxicity and neurodegenerative disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The use of locomotor activity as a behavioral screen for neuronal damage following transient forebrain ischemia in gerbils.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

YM90K, a selective-amino-3-hydroxy5-methyl-4-isoxazole propionate (AMPA) receptor antagonist, prevents induction of heat shock protein HSP -70 and hsp -70 mRNA in rat retrosplenial cortex by phencyclidine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Neuroprotection after several days of mild, drug-induced hypothermia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

NMDA Antagonist Neurotoxicity: Mechanism and Prevention

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The novel sigma ligand JO 1994 protects against ischaemia-induced behavioural changes, cell death and receptor dysfunction in the gerbil.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Effects of Ca2+ and Na+ channel inhibitors in vitro and in global cerebral ischaemia in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

(3SR,4aRS,6RS,8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

(3SR,4aRS,6SR,8aRS)-6-(1H-tetrazol-5-yl)decahydroisoquinoline-3-carboxylic acid, a novel, competitive, systemically active NMDA and AMPA receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Structure-activity studies of 6-(tetrazolylalkyl)-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 1. Effects of stereochemistry, chain length, and chain substitution.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Structure-activity studies of 6-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 2. Effects of distal acid bioisosteric substitution, absolute stereochemical preferences, and in vivo activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Focal cerebral ischaemia in the cat: treatment with the glutamate antagonist MK-801 after induction of ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

AMPA receptor antagonism attenuates MK-801-induced hypermetabolism in the posterior cingulate cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

In vitro and in vivo antagonism of AMPA receptor activation by (3S, 4aR, 6R, 8aR)-6-[2-(1(2)H-tetrazole-5-yl) ethyl] decahydroisoquinoline-3-carboxylic acid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Postischemic diazepam is neuroprotective in the gerbil hippocampus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Endothelin-1 induced middle cerebral artery occlusion: pathological consequences and neuroprotective effects of MK801.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Comparison of the patterns of altered cerebral glucose utilisation produced by competitive and non-competitive NMDA receptor antagonists.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

YM872, a highly water-soluble AMPA receptor antagonist, preserves the hemodynamic penumbra and reduces brain injury after permanent focal ischemia in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The analysis of excitatory, inhibitory and other amino acids in rat brain microdialysates using microbore liquid chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Extracellular striatal dopamine and glutamate after decortication and kainate receptor stimulation, as measured by microdialysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

The GluR5 subtype of kainate receptor regulates excitatory synaptic transmission in areas CA1 and CA3 of the rat hippocampus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Behavioral and histological changes after repeated brief cerebral ischemia by carotid artery occlusion in gerbils.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

AMPA receptor antagonist, YM90K, reduces infarct volume in thrombotic distal middle cerebral artery occlusion in spontaneously hypertensive rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

Postischemic hyperactivity in the Mongolian gerbil correlates with loss of hippocampal neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900250-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0028-3908(99)00250-6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854902%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference