(Q73912480)

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Loss of heterozygosity in spontaneous and X-ray-induced intestinal tumors arising in F1 hybrid min mice: evidence for sequential loss of APC(+) and Dpc4 in tumor development

scientific article published on 01 August 2000

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7 November 2019

Loss of heterozygosity in spontaneous and X-ray-induced intestinal tumors arising in F1 hybrid min mice: evidence for sequential loss of APC(+) and Dpc4 in tumor development (English)

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7 November 2019

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J Haines

1

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7 November 2019

R Dunford

2

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7 November 2019

J Moody

3

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7 November 2019

M Ellender

4

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7 November 2019

R Cox

5

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7 November 2019

A Silver

6

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7 November 2019

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1 August 2000

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7 November 2019

Genes, Chromosomes and Cancer

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7 November 2019

28

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7 November 2019

4

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7 November 2019

387-394

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7 November 2019

Sequence and chromosomal mapping of the mouse homolog (Madh4) of the human DPC4/MADH4 gene.

1 reference

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21 January 2018

Localization of the gene for familial adenomatous polyposis on chromosome 5.

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21 January 2018

Epidemiology of cancer of the colon and rectum

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21 January 2018

Mutations of mitotic checkpoint genes in human cancers

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21 January 2018

Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis

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21 January 2018

Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genes.

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21 January 2018

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

1 reference

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21 January 2018

The intestinal epithelium and its neoplasms: genetic, cellular and tissue interactions

1 reference

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21 January 2018

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

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21 January 2018

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

1 reference

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21 January 2018

A genetic model for colorectal tumorigenesis

1 reference

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21 January 2018

Identification of a chromosome 18q gene that is altered in colorectal cancers

1 reference

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21 January 2018

Molecular biology of colorectal cancer

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21 January 2018

Identification and characterization of the familial adenomatous polyposis coli gene

1 reference

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21 January 2018

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

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21 January 2018

Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP).

1 reference

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21 January 2018

Identification of deletion mutations and three new genes at the familial polyposis locus

1 reference

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21 January 2018

A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18

1 reference

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21 January 2018

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

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21 January 2018

Identification of FAP locus genes from chromosome 5q21

1 reference

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21 January 2018

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

1 reference

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21 January 2018

Mutation and cancer: statistical study of retinoblastoma

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21 January 2018

Loss of constitutional heterozygosity in human cancer.

1 reference

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21 January 2018

Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.

1 reference

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21 January 2018

Somatic genetic events linked to the Apc locus in intestinal adenomas of the Min mouse

1 reference

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21 January 2018

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

1 reference

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21 January 2018

TGF-beta signalling through the Smad pathway

1 reference

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21 January 2018

Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients

1 reference

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21 January 2018

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

1 reference

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21 January 2018

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

1 reference

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21 January 2018

ApcMin: A mouse model for intestinal and mammary tumorigenesis

1 reference

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21 January 2018

Mutations of the APC (adenomatous polyposis coli) gene

1 reference

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21 January 2018

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

1 reference

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21 January 2018

Mutations in the APC gene and their implications for protein structure and function

1 reference

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21 January 2018

APC mutations occur early during colorectal tumorigenesis

1 reference

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21 January 2018

Hereditary gastrointestinal polyposis and nonpolyposis syndromes.

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21 January 2018

A new candidate site for a tumor suppressor gene involved in mouse thymic lymphomagenesis is located on the distal part of chromosome 4

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21 January 2018

Chromosome 5 allele loss in human colorectal carcinomas.

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21 January 2018

The APC gene product in normal and tumor cells

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21 January 2018

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

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21 January 2018

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

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21 January 2018

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

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21 January 2018

Intestinal and extra-intestinal tumor multiplicities in the Apc1638N mouse model after exposure to X-rays.

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21 January 2018

The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in the Apc1638N mouse model

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21 January 2018

Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice

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21 January 2018

Genetic alterations during colorectal-tumor development

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21 January 2018

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10.1002/1098-2264(200008)28:4<387::AID-GCC4>3.0.CO;2-H

1 reference

Europe PubMed Central

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7 November 2019

PubMed publication ID

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Europe PubMed Central

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7 November 2019

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