(Q73937168)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

review article

1 reference

title

Pathogenesis of primary biliary cirrhosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

primary biliary cholangitis

8 November 2019

main subject

0 references

1

David E J Jones

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

publication date

1 October 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

published in

Journal of Hepatology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

639-648

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

Primary biliary cirrhosis once rare, now common in the United Kingdom?

8 November 2019

cites work

1 reference

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7 January 2021

Primary biliary cirrhosis: epidemiology helping the clinician

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7 January 2021

Familial primary biliary cirrhosis reassessed: a geographically-based population study

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7 January 2021

Genetic factors in the pathogenesis of primary biliary cirrhosis

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7 January 2021

Primary biliary cirrhosis: an epidemiological study

1 reference

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7 January 2021

The geographical distribution of primary biliary cirrhosis in a well-defined cohort.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

An exploratory population-based case-control study of primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Risk factors for primary biliary cirrhosis in a cohort of patients from the united states

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

In situ nucleic acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th1 subset

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Identification of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Ductular expression of autoantigens in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

In situ nucleic acid hybridization of pyruvate dehydrogenase complex-E2 in primary biliary cirrhosis: pyruvate dehydrogenase complex-E2 messenger RNA is expressed in hepatocytes but not in biliary epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Expression of antigens related to apoptosis and cell proliferation in chronic nonsuppurative destructive cholangitis in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Bile duct cells in primary biliary cirrhosis are 'primed' for apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Pathogenesis of primary biliary cirrhosis: CD95-induced apoptosis at last?

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Apoptosis of biliary epithelial cells in primary biliary cirrhosis and primary sclerosing cholangitis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Expression of Bcl-2 familial proteins is reduced in small bile duct lesions of primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Enhanced apoptosis relates to bile duct loss in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Fas ligand expressing mononuclear cells around intrahepatic bile ducts co-express CD68 in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Apoptotic pathways in primary biliary cirrhosis and autoimmune hepatitis.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Scavenger cells with gram-positive bacterial lipoteichoic acid infiltrate around the damaged interlobular bile ducts of primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Monocyte chemotactic protein-1, -2, and -3 are distinctively expressed in portal tracts and granulomata in primary biliary cirrhosis: implications for pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Does a betaretrovirus infection trigger primary biliary cirrhosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Expression of pyruvate-dehydrogenase complex PDC-E2 on biliary epithelial cells induced by lymph nodes from primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Human retroviral sequences associated with extracellular particles in autoimmune diseases: epiphenomenon or possible role in aetiopathogenesis?

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Identification of the RPMI 8226 retrovirus and its dissemination as a significant contaminant of some widely used human and marmoset cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Primary biliary cirrhosis showing a high titer of autoantibody; report of a case

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

SEROLOGICAL TESTS IN DIAGNOSIS OF PRIMARY BILIARY CIRRHOSIS

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Primary biliary cirrhosis: identification of two major M2 mitochondrial autoantigens

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Autoantigens in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Natural history of early primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Autoreactive responses to pyruvate dehydrogenase complex in the pathogenesis of primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Human pyruvate dehydrogenase complex as an autoantigen in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Characterization of the autoantibody responses to recombinant E3 binding protein (protein X) of pyruvate dehydrogenase in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Secretory autoantibodies in primary biliary cirrhosis (PBC)

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Mucosal immunity and primary biliary cirrhosis: presence of antimitochondrial antibodies in urine

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Identification and analysis of the major M2 autoantigens in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Reactivity of primary biliary cirrhosis sera with a human fetal liver cDNA clone of branched-chain alpha-keto acid dehydrogenase dihydrolipoamide acyltransferase, the 52 kD mitochondrial autoantigen.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Frequency of IgG and IgM autoantibodies to four specific M2 mitochondrial autoantigens in primary biliary cirrhosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Autoantibodies of sera from patients with primary biliary cirrhosis recognize the alpha subunit of the decarboxylase component of human branched-chain 2-oxo acid dehydrogenase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Three-dimensional structure of the major autoantigen in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Characterisation of the reactivity of autoantibodies in primary biliary cirrhosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Reactivity of primary biliary cirrhosis sera with Escherichia coli dihydrolipoamide acetyltransferase (E2p): characterization of the main immunogenic region

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Lipoylated and unlipoylated domains of human PDC-E2 as autoantigens in primary biliary cirrhosis: significance of lipoate attachment

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Dihydrolipoamide dehydrogenase-binding protein of the human pyruvate dehydrogenase complex. DNA-derived amino acid sequence, expression, and reconstitution of the pyruvate dehydrogenase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Epitope mapping and reactivity of autoantibodies to the E2 component of 2-oxoglutarate dehydrogenase complex in primary biliary cirrhosis using recombinant 2-oxoglutarate dehydrogenase complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Inhibitory autoantibody to a conformational epitope of the pyruvate dehydrogenase complex, the major autoantigen in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Antimitochondrial antibody negative primary biliary cirrhosis: a distinct syndrome of autoimmune cholangitis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Autoantibodies against "nuclear dots" in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Nuclear envelope protein autoantibodies in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Antibodies to carbonic anhydrase in patients with immune cholangiopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Are antibodies to carbonic anhydrase II specific for anti-mitochondrial antibody-negative primary biliary cirrhosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Heterogeneity of autoreactive T cell clones specific for the E2 component of the pyruvate dehydrogenase complex in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

T cell responses to natural human proteins in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Fine specificity of T cells reactive to human PDC-E2 163-176 peptide, the immunodominant autoantigen in primary biliary cirrhosis: implications for molecular mimicry and cross-recognition among mitochondrial autoantigens

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Mimicry peptides of human PDC-E2 163-176 peptide, the immunodominant T-cell epitope of primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

T cell responses to the putative dominant autoepitope in primary biliary cirrhosis (PBC)

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Pyruvate dehydrogenase specific T cells in primary biliary cirrhosis show restricted antigen recognition sites

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

The liver as a crucial organ in the first line of host defense: the roles of Kupffer cells, natural killer (NK) cells and NK1.1 Ag+ T cells in T helper 1 immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Immunization of experimental animals with dihydrolipoamide acetyltransferase, as a purified recombinant polypeptide, generates mitochondrial antibodies but not primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Experimental autoimmune cholangitis: a mouse model of immune-mediated cholangiopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Breakdown of tolerance to pyruvate dehydrogenase complex in experimental autoimmune cholangitis: a mouse model of primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Investigation of a mechanism for accelerated breakdown of immune tolerance to the primary biliary cirrhosis-associated autoantigen, pyruvate dehydrogenase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

The SJL/J mouse is not a model for PBC

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Sera from patients with tuberculosis recognize the M2a-epitope (E2-subunit of pyruvate dehydrogenase) specific for primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Bacterial motif DNA as an adjuvant for the breakdown of immune self-tolerance to pyruvate dehydrogenase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Low avidity recognition of self-antigen by T cells permits escape from central tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2803%2900270-8

7 January 2021

10.1016/S0168-8278(03)00270-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12971978%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference