(Q74023929)

English

Inhibition of neutrophil migration soon after initiation of treatment with leflunomide or methotrexate in patients with rheumatoid arthritis: findings in a prospective, randomized, double-blind clinical trial in fifteen patients

scientific article published on 01 July 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10902750%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Inhibition of neutrophil migration soon after initiation of treatment with leflunomide or methotrexate in patients with rheumatoid arthritis: findings in a prospective, randomized, double-blind clinical trial in fifteen patients (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10902750%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

double-blind clinical trial

1 reference

based on heuristic

inferred from title

rheumatoid arthritis

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Kraan MC

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10902750%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

de Koster BM

2

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Europe PubMed Central

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8 November 2019

Elferink JG

3

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8 November 2019

Post WJ

4

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8 November 2019

Breedveld FC

5

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8 November 2019

Tak PP

6

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8 November 2019

publication date

1 July 2000

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8 November 2019

Arthritis and Rheumatism

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10902750%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

43

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8 November 2019

7

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8 November 2019

1488-1495

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PubMed publication ID

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8 November 2019

Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial. European Leflunomide Study Group.

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200007%2943%3A7%3C1488%3A%3AAID-ANR11%3E3.0.CO%3B2-G

21 January 2018

Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators Group

1 reference

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21 January 2018

The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase

1 reference

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21 January 2018

Functional expression of a fragment of human dihydroorotate dehydrogenase by means of the baculovirus expression vector system, and kinetic investigation of the purified recombinant enzyme

1 reference

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21 January 2018

Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives

1 reference

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21 January 2018

Dihydroorotate dehydrogenase is a high affinity binding protein for A77 1726 and mediator of a range of biological effects of the immunomodulatory compound

1 reference

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21 January 2018

Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation

1 reference

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21 January 2018

Inhibition of the epidermal growth factor receptor tyrosine kinase activity by leflunomide

1 reference

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21 January 2018

Regulation of B cell function by the immunosuppressive agent leflunomide

1 reference

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21 January 2018

Effects of leflunomide and other immunosuppressive agents on T cell proliferation in vitro

1 reference

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21 January 2018

Effect of leflunomide on constitutive and inducible pathways of cellular eicosanoid generation

1 reference

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21 January 2018

Degradation of human articular cartilage by neutrophils in synovial fluid

1 reference

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21 January 2018

Total Leukocyte Enumeration in Pathologic Synovial Fluids

1 reference

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21 January 2018

Rheumatoid synovial fibroblast adhesion to human articular cartilage. Enhancement by neutrophil proteases

1 reference

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21 January 2018

Effects of pulse methylprednisolone on cell adhesion molecules in the synovial membrane in rheumatoid arthritis. Reduced E-selectin and intercellular adhesion molecule 1 expression

1 reference

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21 January 2018

Potentiation and inhibition of migration of human neutrophils by auranofin

1 reference

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21 January 2018

Effects of methotrexate, sulphasalazine and aurothiomalate on polymorphonuclear leucocytes in rheumatoid arthritis

1 reference

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21 January 2018

Inhibition of human neutrophils by auranofin: chemotaxis and metabolism of arachidonate via the 5-lipoxygenase pathway

1 reference

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21 January 2018

Inhibition of neutrophil chemotaxis in methotrexate-treated rheumatoid arthritis patients

1 reference

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21 January 2018

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1 reference

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21 January 2018

American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis

1 reference

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21 January 2018

Migratory activity of blood polymorphonuclear leukocytes during juvenile rheumatoid arthritis, demonstrated with a new whole-blood membrane filter assay

1 reference

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21 January 2018

The effect of endothelin-2 (ET-2) on migration and changes in cytosolic free calcium of neutrophils

1 reference

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21 January 2018

Neutrophil chemotaxis induced by the diacylglycerol kinase inhibitor R59022

1 reference

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21 January 2018

Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate

1 reference

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21 January 2018

Methotrexate inhibits polymorphonuclear leucocyte chemotaxis in psoriasis

1 reference

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21 January 2018

Pharmacologic manipulation of leukocyte chemotaxis. Present knowledge and future trends

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21 January 2018

Increased Level of Dihydrofolic Reductase in Leucocytes of Patients Treated with Amethopterin

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21 January 2018

Increase of dihydrofolate reductase in peripheral blood lymphocytes of rheumatoid arthritis patients treated with low-dose oral methotrexate.

1 reference

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21 January 2018

Polyglutamation of methotrexate. Is methotrexate a prodrug?

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21 January 2018

Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow

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21 January 2018

Inhibition of Protein Tyrosine Phosphorylation in T Cells by a Novel Immunosuppressive Agent, Leflunomide

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21 January 2018

Structural and functional comparison of agents interfering with dihydroorotate, succinate and NADH oxidation of rat liver mitochondria

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21 January 2018

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Purines and neutrophil leukocytes

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21 January 2018

Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor alpha monoclonal antibody treatment in patients with rheumatoid arthritis

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21 January 2018

Methotrexate reduces inflammatory cell numbers, expression of monokines and of adhesion molecules in synovial tissue of patients with rheumatoid arthritis

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21 January 2018

Expression of Adhesion Molecules in Early Rheumatoid Synovial Tissue

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21 January 2018

Neutrophil trafficking into inflamed joints in patients with rheumatoid arthritis, and the effects of methylprednisolone

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21 January 2018

Neutrophil expression of tumour necrosis factor receptors (TNF-R) and of activation markers (CD11b, CD43, CD63) in rheumatoid arthritis

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21 January 2018

Identifiers

10.1002/1529-0131(200007)43:7<1488::AID-ANR11>3.0.CO;2-G

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10902750%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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