(Q74075555)

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Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation

scientific article published on 01 February 1998

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

S Cuzzocrea

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

B Zingarelli

2

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

P Hake

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

A L Salzman

4

1 reference

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

C Szabó

5

1 reference

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8 November 2019

publication date

1 February 1998

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Free Radical Biology and Medicine

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

24

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

450-459

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Nitric oxide as a secretory product of mammalian cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective pharmacological inhibition of distinct nitric oxide synthase isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Reactions between nitric oxide, superoxide, and peroxynitrite: footprints of peroxynitrite in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of superoxide-dependent oxidation and hydroxylation reactions by nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Therapeutic strategies for the inhibition of inducible nitric oxide synthase--potential for a novel class of anti-inflammatory agents

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The inhibitory effects of mercaptoalkylguanidines on cyclo-oxygenase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemical protection against ionizing radiation. III. Mercaptoalkylguanidines and related isothiuronium compounds with protective activity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered immune responses in mice lacking inducible nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Zymosan-activated plasma induces paw oedema by nitric oxide and prostaglandin production.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Screens for anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Low levels of reactive oxygen species as modulators of cell function

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Redox regulation of transcriptional activators

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of the expression of inducible nitric oxide synthase by aminoguanidine or aminoethyl-isothiourea in macrophages and in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interactions of nitric oxide with cyclooxygenase: in vitro, ex vivo, and in vivo studies

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide enhances cyclooxygenase activity in articular cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Neutrophil enzyme activities in carrageenan-induced inflammation in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacological demonstration of inflammatory mediators using experimental inflammatory models: rat pleurisy induced by carrageenin and phorbol myristate acetate

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Release of 15-hydroxy-5,8,11,13-eicosatetraenoic acid and cysteinyl-leukotrienes in carrageenin-induced inflammation: effect of non-steroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Depression of the inotropic action of isoprenaline by nitric oxide synthase induction in rat isolated hearts.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of oxidant injury of cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2897%2900280-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0891-5849(97)00280-3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9438558%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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