(Q74238266)

English

Heterogeneous ligand-mediated Ca(++) responses at wt and mutant alpha(2A)-adrenoceptors suggest multiple ligand activation binding sites at the alpha(2A)-adrenoceptor

scientific article published on 01 August 2000

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scholarly article

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9 November 2019

Heterogeneous ligand-mediated Ca(++) responses at wt and mutant alpha(2A)-adrenoceptors suggest multiple ligand activation binding sites at the alpha(2A)-adrenoceptor (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10963753%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

P J Pauwels

1

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9 November 2019

F C Colpaert

2

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9 November 2019

publication date

1 August 2000

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9 November 2019

Neuropharmacology

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9 November 2019

39

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9 November 2019

11

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9 November 2019

2101-2111

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9 November 2019

Abnormal regulation of the sympathetic nervous system in alpha2A-adrenergic receptor knockout mice.

1 reference

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Selective inhibition of adenylyl cyclase by octopamine via a human cloned alpha 2A-adrenoceptor

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

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Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function

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Adrenergic Receptors From Molecular Structure to in vivo function

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Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding

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7 January 2021

Central hypotensive effects of the alpha2a-adrenergic receptor subtype.

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G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

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Pharmacology of cloned human 5-HT1D receptor-mediated functional responses in stably transfected rat C6-glial cell lines: further evidence differentiating human 5-HT1D and 5-HT1B receptors

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7 January 2021

The effect of site-directed mutagenesis of two transmembrane serine residues on agonist-specific coupling of a cloned human alpha2A-adrenoceptor to adenylyl cyclase

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A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents

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G-protein activation by putative antagonists at mutant Thr373Lys alpha2A adrenergic receptors

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Identifiers

10.1016/S0028-3908(00)00040-X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10963753%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

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9 November 2019

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