(Q74284137)

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Synthetic peptides that inhibit binding of the myelin basic protein 85-99 epitope to multiple sclerosis-associated HLA-DR2 molecules and MBP-specific T-cell responses

scientific article published on 01 August 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Synthetic peptides that inhibit binding of the myelin basic protein 85-99 epitope to multiple sclerosis-associated HLA-DR2 molecules and MBP-specific T-cell responses (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

M Fridkis-Hareli

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

L Fugger

3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

publication date

1 August 2001

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Human Immunology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

62

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

8

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9 November 2019

753-763

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

The genetics of susceptibility to multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The HLA-Dw2 haplotype segregates closely with multiple sclerosis in multiplex families

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Major T-cell responses in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

T-cell recognition of myelin basic protein

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation and characterization of autoreactive proteolipid protein-peptide specific T-cell clones from multiple sclerosis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: reactivity to the extracellular domain of MOG is directed against three main regions

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of relapsing paralysis in experimental autoimmune encephalomyelitis by bacterial superantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

T cells responsive to myelin basic protein in patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A Molecular Basis for MHC Class II—Associated Autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence analysis of peptides bound to MHC class II molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a motif for HLA-DR1 binding peptides using M13 display libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Promiscuous and allele-specific anchors in HLA-DR-binding peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Natural peptide ligand motifs of two HLA molecules associated with myasthenia gravis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of autoimmune diabetes in non-obese diabetic mice by treatment with a class II major histocompatibility complex-blocking peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression by several synthetic polypeptides of experimental allergic encephalomyelitis induced in guinea pigs and rabbits with bovine and human basic encephalitogen

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of experimental allergic encephalomyelitis in Rhesus monkeys by a synthetic basic copolymer.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

T suppressor hybridomas and interleukin-2-dependent lines induced by copolymer 1 or by spinal cord homogenate down-regulate experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A pilot trial of Cop 1 in exacerbating-remitting multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability. Copolymer 1 Multiple Sclerosis Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Binding of random copolymers of three amino acids to class II MHC molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthetic peptides that inhibit binding of the collagen type II 261-273 epitope to rheumatoid arthritis-associated HLA-DR1 and -DR4 molecules and collagen-specific T-cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of recombinant HLA-DR2 molecules. Replacement of the hydrophobic transmembrane region by a leucine zipper dimerization motif allows the assembly and secretion of soluble DR alpha beta heterodimers.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells--specificity and promiscuity.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clones

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Copolymer 1 acts against the immunodominant epitope 82-100 of myelin basic protein by T cell receptor antagonism in addition to major histocompatibility complex blocking

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2801%2900279-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0198-8859(01)00279-8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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