(Q74293279)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495564%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

review article

1 reference

title

The role of the phosphoinositide signalling system in the pathogenesis of sporadic Alzheimer's disease: a hypothesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495564%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

C J Fowler

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495564%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

publication date

1 December 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495564%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495564%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495564%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

373-380

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495564%20AND%20SRC:MED&resulttype=core&format=json

The iron-binding and hydroxyl radical scavenging action of anti-inflammatory drugs

9 November 2019

cites work

1 reference

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7 January 2021

Hydrogen peroxide mediates amyloid beta protein toxicity

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7 January 2021

Are reactive oxygen species involved in Alzheimer's disease?

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7 January 2021

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

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7 January 2021

Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with a constitutive up-regulation of protein kinase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Action of amyloid beta-protein on protein kinase C activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Decreased levels of protein kinase C in Alzheimer brain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Adenylyl cyclase activity in postmortem human brain: evidence of altered G protein mediation in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Cholinergic and serotonergic stimulation of phosphoinositide hydrolysis is decreased in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Area specific alterations in muscarinic stimulated low Km GTPase activity in aging and Alzheimer's disease: implications for altered signal transduction

1 reference

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7 January 2021

Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Diminished muscarinic receptor-stimulated [3H]-PIP2 hydrolysis in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Stimulation of inositol phospholipid breakdown in rat cortical and hippocampal miniprisms by noradrenaline, 5-hydroxytryptamine and carbachol: some methodological aspects

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Diminished [3H]inositol(1,4,5)P3 but not [3H]inositol(1,3,4,5)P4 binding in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain

1 reference

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7 January 2021

Phosphoinositide hydrolysis, G alpha q, phospholipase C, and protein kinase C in post mortem human brain: effects of post mortem interval, subject age, and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Copper ions and diamide induce a high affinity guanine-nucleotide-insensitive state for muscarinic agonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Decreased inositol (1,4,5)-trisphosphate receptor levels in Alzheimer's disease cerebral cortex: selectivity of changes and possible correlation to pathological severity.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Cholinergic activation of phosphoinositide signaling is impaired in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

In vivo or in vitro administration of the nitrone spin-trapping compound, n-tert-butyl-alpha-phenylnitrone, (PBN) reduces age-related deficits in striatal muscarinic receptor sensitivity.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Selective cross-activation/inhibition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perifused rat striata.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Modulation of bradykinin-induced calcium signals by oxidative stress in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Effects of postmortem interval, age, and Alzheimer's disease on G-proteins in human brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Calcium-induced degradation of the inositol (1,4,5)-trisphosphate receptor/Ca(2+)-channel.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Protein kinase C alteration is an early biochemical marker in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Differential involvement of protein kinase C isozymes in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Ca2+-dependent and Ca2+-independent protein kinase C changes in the brain of patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Priming of monocyte respiratory burst by beta-amyloid fragment (25-35)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Phorbol esters but not the cholinergic agonists oxotremorine-M and carbachol increase release of the amyloid precursor protein in cultured rat cortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Protein kinase C: structure, function, and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Regionally selective alterations in G protein subunit levels in the Alzheimer's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Aberrant protein kinase C cascades in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Assessment of protein kinase C isozymes by two-site enzyme immunoassay in human brains and changes in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Guanine nucleotide modulation of muscarinic cholinergic receptor binding in postmortem human brain--a preliminary study in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Radical AGEing in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Reduced phosphoinositide concentrations in anterior temporal cortex of Alzheimer-diseased brains.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Effect of thiol reagents on phosphoinositide hydrolysis in rat brain synaptoneurosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Attenuated protein kinase C activity and translocation in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Deleterious network: a testable pathogenetic concept of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

Decreased brain [3H]inositol 1,4,5-trisphosphate binding in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0173%2897%2900024-6

7 January 2021

10.1016/S0165-0173(97)00024-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495564%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference