(Q74339183)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995836%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity (English)

1 reference

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10 November 2019

1 reference

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2

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10 November 2019

author name string

I I Kruman

1

1 reference

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10 November 2019

S L Chan

3

1 reference

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10 November 2019

Y Kruman

4

1 reference

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10 November 2019

Z Guo

5

1 reference

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10 November 2019

L Penix

6

1 reference

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10 November 2019

M P Mattson

7

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10 November 2019

publication date

1 September 2000

1 reference

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10 November 2019

published in

Journal of Neuroscience

1 reference

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10 November 2019

volume

20

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10 November 2019

issue

18

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10 November 2019

page(s)

6920-6926

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995836%20AND%20SRC:MED&resulttype=core&format=json

Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status

10 November 2019

cites work

1 reference

12 December 2020

Pathobiology of ischaemic stroke: an integrated view

1 reference

12 December 2020

Poly (ADP-ribose) polymerase, nitric oxide and cell death

1 reference

12 December 2020

Apoptosis and expression of DNA repair proteins in ischaemic brain injury in man.

1 reference

12 December 2020

DNA strand breaks in Alzheimer's disease.

1 reference

12 December 2020

Characterization of the stress-inducing effects of homocysteine

1 reference

12 December 2020

Neuronal loss and synaptic reorganization in temporal lobe epilepsy

1 reference

12 December 2020

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine

1 reference

12 December 2020

Immunohistochemical evidence for apoptosis in Alzheimer's disease.

1 reference

12 December 2020

Optimization of single-cell gel electrophoresis (SCGE) for quantitative analysis of neuronal DNA damage.

1 reference

12 December 2020

Life and death of neurons in the aging brain

1 reference

12 December 2020

P53- and CD95-associated apoptosis in neurodegenerative diseases

1 reference

12 December 2020

Differential radiosensitivity of neurons and neuroglia of the hippocampus in the adult rabbit

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12 December 2020

A caspase-activated factor (CAF) induces mitochondrial membrane depolarization and cytochrome c release by a nonproteolytic mechanism.

1 reference

12 December 2020

Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor

1 reference

12 December 2020

Folic acid, homocysteine and one-carbon metabolism: a review of the essential biochemistry

1 reference

12 December 2020

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

12 December 2020

Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis.

1 reference

12 December 2020

Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission

1 reference

12 December 2020

Hyperhomocysteinaemia; with reference to its neuroradiological aspects

1 reference

12 December 2020

A role for the tumour suppressor gene p53 in regulating neuronal apoptosis

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12 December 2020

Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation.

1 reference

12 December 2020

Stroke risk factors and stroke prevention

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12 December 2020

Homocysteine and cardiovascular disease

1 reference

12 December 2020

GADD45 is induced in Alzheimer's disease, and protects against apoptosis in vitro

1 reference

12 December 2020

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

1 reference

12 December 2020

Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

1 reference

12 December 2020

Homocysteine and vascular disease: nature or nurture?

1 reference

12 December 2020

Homocysteine and cysteine: determinants of plasma levels in middle-aged and elderly subjects

1 reference

12 December 2020

Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

1 reference

12 December 2020

Neuronal necrosis and apoptosis: two distinct events induced by exposure to glutamate or oxidative stress.

1 reference

12 December 2020

Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury

1 reference

12 December 2020

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

12 December 2020

Serum folate and risk for ischemic stroke. First National Health and Nutrition Examination Survey epidemiologic follow-up study

1 reference

12 December 2020

Functional methionine synthase deficiency (cblE and cblG): clinical and biochemical heterogeneity

1 reference

12 December 2020

Ischemic brain damage and memory impairment: a commentary

1 reference

12 December 2020

Cerebrospinal fluid and plasma total homocysteine and related metabolites in children with cystathionine beta-synthase deficiency: the effect of treatment

1 reference

12 December 2020

B vitamins, homocysteine, and neurocognitive function in the elderly

1 reference

12 December 2020

Increases in DNA lesions and the DNA damage indicator Gadd45 following transient cerebral ischemia

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12 December 2020

Homocysteine mediated endothelial cell toxicity and its amelioration

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12 December 2020

Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure

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12 December 2020

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

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12 December 2020

The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons.

1 reference

12 December 2020

Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.

1 reference

12 December 2020

Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons

1 reference

12 December 2020

Methionine metabolism in mammals

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12 December 2020

Homocysteine and Alzheimer's disease.

1 reference

12 December 2020

Nuclear accumulation of p53 protein following kainic acid-induced seizures.

1 reference

12 December 2020

Hippocampal Myc and p53 expression following transient global ischemia

1 reference

12 December 2020

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

1 reference

12 December 2020

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

1 reference

12 December 2020

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1 reference

12 December 2020

Activation of poly [ADP-Ribose] polymerase in endothelial cells and keratinocytes: role in an in vitro model of sulfur mustard-mediated vesication

1 reference

12 December 2020

Evidence for synaptic apoptosis.

1 reference

12 December 2020

The amyloid beta protein induces oxidative damage of mitochondrial DNA.

1 reference

12 December 2020

Bax involvement in p53-mediated neuronal cell death

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12 December 2020

Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.

1 reference

12 December 2020

Synaptosomal plasma membrane transport of excitatory sulphur amino acid transmitter candidates: kinetic characterisation and analysis of carrier specificity

1 reference

12 December 2020

An improved cycling assay for nicotinamide adenine dinucleotide.

1 reference

12 December 2020

Homocysteine and atherothrombosis

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12 December 2020

Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.

1 reference

12 December 2020

Control of DNA Repair Linked to Neuroblastoma Differentiation

1 reference

12 December 2020

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

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12 December 2020

Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture

1 reference

12 December 2020

Mitochondrial depolarization is not required for neuronal apoptosis.

1 reference

12 December 2020

10.1523/JNEUROSCI.20-18-06920.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995836%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995836%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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