(Q74638217)

English

Suboptimal cross-linking of antigen receptor induces Syk-dependent activation of p70S6 kinase through protein kinase C and phosphoinositol 3-kinase

scientific article published on 01 April 1999

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Suboptimal cross-linking of antigen receptor induces Syk-dependent activation of p70S6 kinase through protein kinase C and phosphoinositol 3-kinase (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

H L Li

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

W Davis

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

E Puré

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

language of work or name

0 references

publication date

1 April 1999

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

274

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

14

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

9812-9820

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Syk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mitogen-activated protein kinase-independent pathway in B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

p70s6k function is essential for G1 progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Inhibition of human B lymphocyte cell cycle progression and differentiation by rapamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Differential activation of mitogen-activated protein kinase and S6 kinase signaling pathways by 12-O-tetradecanoylphorbol-13-acetate (TPA) and insulin. Evidence for involvement of a TPA-stimulated protein-tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

p42 mitogen-activated protein kinase and p90 ribosomal S6 kinase are selectively phosphorylated and activated during thrombin-induced platelet activation and aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Activation of S6 kinase in human neutrophils by calcium pyrophosphate dihydrate crystals: protein kinase C-dependent and phosphatidylinositol-3-kinase-independent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Wortmannin-sensitive activation of p70S6-kinase and MAP-kinase by the G protein-coupled receptor, G/CCKB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Requirement for phosphoinositide 3-OH kinase in growth hormone signalling to the mitogen-activated protein kinase and p70s6k pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Syk tyrosine kinase required for mouse viability and B-cell development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Association of p72syk with the src homology-2 (SH2) domains of PLC gamma 1 in B lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Insulin stimulation of mitogen-activated protein kinase, p90rsk, and p70 S6 kinase in skeletal muscle of normal and insulin-resistant mice. Implications for the regulation of glycogen synthase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Phosphorylation of elongation factor 1 and ribosomal protein S6 by multipotential S6 kinase and insulin stimulation of translational elongation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play a role?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Activation of protein kinase C triggers its ubiquitination and degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

B-cell activation versus tolerance--the central role of immunoglobulin receptor engagement and T-cell help

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Multiple independent inputs are required for activation of the p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Divergent functional roles for p90rsk kinase domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

The modular phosphorylation and activation of p70s6k.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Structural and functional analysis of pp70S6k

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

TOR signalling and control of cell growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Mechanism of action of the immunosuppressant rapamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9812

21 January 2018

Identifiers

10.1074/JBC.274.14.9812

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10092671%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q74638217&oldid=1612401631"