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The thymus and negative selection
scientific article published on 01 July 2002
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
The thymus and negative selection
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author
Jonathan Sprent
series ordinal
1
object named as
Jonathan Sprent
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
Hidehiro Kishimoto
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
publication date
1 July 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
Immunological Reviews
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
185
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
126-135
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
cites work
Discovering the origins of immunological competence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell tolerance by clonal elimination in the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell tolerance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance and ways to break it.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Central tolerance of T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrathymic and extrathymic clonal deletion of T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positive selection of T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental biology of T cells in T cell-receptor transgenic mice
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Crossref
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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
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7 January 2021
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Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative selection in the thymus includes semimature T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Killing of immature CD4+ CD8+ thymocytes in vivo by anti-CD3 or 5'-(N-ethyl)-carboxamide adenosine is blocked by glucocorticoid receptor antagonist RU-486
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen-specific and nonspecific deletion of immature cortical thymocytes caused by antigen injection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Does T-cell tolerance require a dedicated antigen-presenting cell?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell apoptosis detected in situ during positive and negative selection in the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for Fas in negative selection of thymocytes in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of fas death signals by FLIPs
1 reference
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Crossref
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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Several different cell surface molecules control negative selection of medullary thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-dependent diabetes mellitus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoimmunity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
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7 January 2021
based on heuristic
inferred from DOI database lookup
A new look at MHC and autoimmune disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC structure and autoimmune T cell repertoire development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A defect in central tolerance in NOD mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor editing in developing T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell memory
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2 family members and the mitochondria in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The frequency of high avidity T cells determines the hierarchy of determinant spreading
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance to islet autoantigens in type 1 diabetes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cells in autoimmmunity*.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cells: key controllers of immunologic self-tolerance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of immune pathology by regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18512.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1034/J.1600-065X.2002.18512.X
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PubMed ID
12190927
1 reference
stated in
Europe PubMed Central
PubMed ID
12190927
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12190927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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