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Telomeres, the nucleolus and aging
scientific article published on 01 June 1998
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scholarly article
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Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
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12 November 2019
review article
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Europe PubMed Central
title
Telomeres, the nucleolus and aging
(English)
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Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
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12 November 2019
author
Leonard P. Guarente
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L Guarente
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Europe PubMed Central
PubMed publication ID
9640533
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
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12 November 2019
author name string
F B Johnson
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1
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Europe PubMed Central
PubMed publication ID
9640533
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12 November 2019
R A Marciniak
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2
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Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
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12 November 2019
publication date
1 June 1998
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Europe PubMed Central
PubMed publication ID
9640533
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12 November 2019
published in
Current Opinion in Cell Biology
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stated in
Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
10
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Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
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12 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
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12 November 2019
page(s)
332-338
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Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
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12 November 2019
cites work
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomeres shorten during ageing of human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
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inferred from DOI database lookup
In vivo loss of telomeric repeats with age in humans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of life-span by introduction of telomerase into normal human cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
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Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The telomere hypothesis of cellular aging
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase catalytic subunit homologs from fission yeast and human
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase activity: a biomarker of cell proliferation, not malignant transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere length and replicative aging in human vascular tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Similar, but not identical, modulation of expression of extracellular matrix components during in vitro and in vivo aging of human skin fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterogeneity in telomere length of human chromosomes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase activity in normal and malignant hematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase activity concentrates in the mitotically active segments of human hair follicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase activity is induced by the stimulation to antigen receptor in human peripheral lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Up-regulation of telomerase activity in human lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated expression of telomerase activity in human T lymphocyte development and activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere lengthening and telomerase activation during human B cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein-counting mechanism for telomere length regulation in yeast.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of telomere length by the human telomeric protein TRF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere length constancy during aging of Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human homologues of yeast helicase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extrachromosomal rDNA circles--a cause of aging in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extrachromosomal circular DNAs and genomic sequence plasticity in eukaryotic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related increase in methylation of ribosomal genes and inactivation of chromosome-specific rRNA gene clusters in mouse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased synthesis of nucleolar RNA in aging human cells in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A longitudinal study of human age-related ribosomal RNA gene activity as detected by silver-stained NORs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo telomere dynamics of human hematopoietic stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of hybridizable ribosomal DNA from human post-mitotic tissues during aging: I. Age-dependent loss in human myocardium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of hybridizable ribosomal DNA from human post-mitotic tissues during aging: II. Age-dependent loss in human cerebral cortex — Hippocampal and somatosensory cortex comparison
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constancy of ribosomal RNA genes during aging of mouse heart cells and during serial passage of WI-38 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase and cancer: revisiting the telomere hypothesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980008-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0955-0674(98)80008-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PubMed publication ID
9640533
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9640533
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9640533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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