(Q74801893)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

review article

1 reference

title

Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

main subject

hepatocellular carcinoma

1 reference

1

S Knasmüller

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

author name string

W Parzefall

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

R Sanyal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

S Ecker

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

C Schwab

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

M Uhl

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

V Mersch-Sundermann

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

G Williamson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

G Hietsch

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

T Langer

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

F Darroudi

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

A T Natarajan

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

language of work or name

English

0 references

publication date

1 June 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

volume

402

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

issue

1-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

page(s)

185-202

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

Limitations of metabolic activation systems used with in vitro tests for carcinogens

13 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Mutagenicity testing with the Salmonella/hepatocyte and the Salmonella/microsome assays. A comparative study with some known genotoxic compounds.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Human hepatocytes in genotoxicity assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Evaluation studies on the in vitro rat hepatocyte micronucleus assay.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Induction of sister chromatid exchanges in cultured adult rat hepatocytes by directly and indirectly acting mutagens/carcinogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Modulation of functional activities in cultured rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Maintenance of microsomal cytochromes b5 and P-450 in primary cultures of parenchymal liver cells on collagen membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Genotoxicity assessment of aromatic amines and amides in genetically engineered V79 cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Mutagenicity, clastogenicity and cytotoxicity of procarcinogens in a rat hepatoma cell line competent for xenobiotic metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Sister-chromatid exchange induction by carcinogens in HTC cells: an in vitro system which does not require addition of activating factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Activation of polycyclic hydrocarbons in Reuber H4-II-E hepatoma cells an in vitro system for the induction of SCEs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Sister-chromatid exchange induction by polycyclic aromatic hydrocarbons in an intact cell system of adult rat-liver epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Differences in responses of 4 adult rat-liver epithelial cell lines to a spectrum of chemical mutagens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Induction of sister-chromatid exchanges by procarcinogens in metabolically competent Chinese hamster epithelial liver cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Divergence of metabolic activation systems for short-term mutagenesis assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Primary cultures and the levels of cytochrome P450 in hepatocytes from mouse, rat, hamster, and rabbit liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Use of an established human hepatoma cell line with endogenous bioactivation for gene mutation studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Increased cytotoxicity of 3-morpholinosydnonimine to HepG2 cells in the presence of superoxide dismutase. Role of hydrogen peroxide and iron

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

In vitro assessment of the ethanol-induced hepatotoxicity on HepG2 cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Characterization of the role of individual protein binding motifs within the hepatitis B virus enhancer I on X promoter activity using linker scanning mutagenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Dioxin receptor and C/EBP regulate the function of the glutathione S-transferase Ya gene xenobiotic response element

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Identification of dioxin-responsive genes in Hep G2 cells using differential mRNA display RT-PCR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Characterization of the human surfactant protein D promoter: transcriptional regulation of SP-D gene expression by glucocorticoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Transcriptional regulation of the gene coding for human protein C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Drug metabolism by the human hepatoma cell, Hep G2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Metabolic activation of benzo[a]pyrene by a human hepatoma cell line.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Mixed function oxidase and UDP-glucuronyltransferase activities in the human Hep G2 hepatoma cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

The influence of culture medium composition on drug metabolising enzyme activities of the human liver derived Hep G2 cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

HepG2 cells: an in vitro model for P450-dependent metabolism of acetaminophen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Metabolic activation by a supernatant from human hepatoma cells: a possible alternative in mutagenic tests

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Evaluation of a human hepatoma cell line as a target cell in genetic toxicology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Enzymic sulphation of dopa and tyrosine isomers by HepG2 human hepatoma cells: stereoselectivity and stimulation by Mn2+.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

De novo sulfation of L-tyrosine in HepG2 human hepatoma cells and its possible functional implication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Human phenol sulfotransferases: chiral substrates and expression in Hep G2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Arylamine N-acetyltransferase activity in human cultured cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

The effects of inducing agents on cytochrome P450 and UDP-glucuronyltransferase activities in human HEPG2 hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Acute cytotoxicities of polynuclear aromatic hydrocarbons determined in vitro with the human liver tumor cell line, HepG2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Induction of aryl hydrocarbon hydroxylase and demonstration of a specific nuclear receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in two human hepatoma cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Effect of enzyme inducers on metabolism of 1-nitropyrene in human hepatoma cell line HepG2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Status of reduced glutathione in the human hepatoma cell line, HEP G2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Mutagenic activation of aromatic amines by a human hepatoma cell (Hep G2) supernatant tested by means of Salmonella typhimurium strains with different acetyltransferase activities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Sensitive method for the detection of mutagenic nitroarenes and aromatic amines: new derivatives of Salmonella typhimurium tester strains possessing elevated O-acetyltransferase levels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Metabolic activation of chemicals to mutagenic carcinogens by human hepatoma microsomal extracts in Chinese hamster ovary cells (in vitro)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Revised methods for the Salmonella mutagenicity test

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Mutagenicities of N-nitrosamines on salmonella

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Detection of aneugenic and clastogenic potential of X-rays, directly and indirectly acting chemicals in human hepatoma (Hep G2) and peripheral blood lymphocytes, using the micronucleus assay and fluorescent in situ hybridization with a DNA centromer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Use of the human liver cell line Hep G2 in a modified Salmonella reversion assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Frequency of sister chromatid exchanges in human lymphocytes cultivated with a human hepatoma cell line as an indicator of the carcinogenic potency of two cyclopenta[a]phenanthrenes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Mutagenic activity of methyl- and fluoro-substituted derivatives of polycyclic aromatic hydrocarbons in a human hepatoma (HepG2) cell-mediated assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Effect of eugenol on the genotoxicity of established mutagens in the liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Human bioassays to assess environmental genotoxicity: development of a DNA break bioassay in HepG2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Differential sensitivity of human hepatoma cell line and primary rat hepatocyte culture to benzo(a)pyrene-induced unscheduled DNA synthesis and adduct formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Human bioassays to assess environmental genotoxicity: development of a DNA repair assay in HepG2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Pathways for the mutagenesis of 1-nitropyrene and dinitropyrenes in the human hepatoma cell line HepG2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Induction of sister chromatid exchanges by benzidine in rat and human hepatoma cell lines and inhibition by indomethacin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Cytogenetic effects of the antichagasic benznidazole on human cells in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Induction of sister chromatid exchanges in human and rat hepatoma cell lines by cyclophosphamide and phosphoramide mustard and the effects of cytochrome P-450 inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

The anticlastogenicity of beta-carotene evaluated on human hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Inhibition of the genotoxic effects of heterocyclic amines in human derived hepatoma cells by dietary bioantimutagens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Genotoxicity of 1,3- and 1,6-dinitropyrene: induction of micronuclei in a panel of mammalian test cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Differential mutagenic activity of IQ (2-amino-3-methylimidazo[4,5-f]quinoline) in Salmonella typhimurium strains in vitro and in vivo, in Drosophila, and in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

An experimental approach to identifying the genotoxic risk from cooked meat mutagens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

In vivo cytogenetic effects of cooked food mutagens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Antimutagens. Data and problems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Antimutagens as cancer chemopreventive agents in the diet

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Mechanisms of inhibitors of mutagenesis and carcinogenesis. Classification and overview

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Effects of ethanol treatment on DNA damage induced in Escherichia coli K-12 in various organs of mice by N-nitro-sonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosopyrrolidine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Effects of phenethyl isothiocyanate on metabolism and on genotoxicity of dimethylnitrosamine and 2-amino-1-methyl-6-phenylimidazo[4, 5-beta]pyridine (PhIP).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Modification of genotoxicity by naturally occurring flavorings and their derivatives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Regulatory elements controlling the basal and drug-inducible expression of glutathione S-transferase Ya subunit gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Effect of diallyl sulfide, a naturally occurring anti-carcinogen, on glutathione-dependent detoxification enzymes of female CD-1 mouse tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

A comparative study of five nitro musk compounds for genotoxicity in the SOS chromotest and Salmonella mutagenicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Nitro musks are cogenotoxicants by inducing toxifying enzymes in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

Mutational analysis of the cysteine residues in the hepatitis B virus small envelope protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Characterization and genetic analysis of alternatively spliced transcripts of hepatitis B virus in infected human liver tissues and transfected HepG2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900297-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0027-5107(97)00297-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9675276%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

1 reference