(Q76378542)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

review article

1 reference

title

[Molecular mechanisms of amyotrophic lateral sclerosis: recent contributions from studies in animal models] (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

24 November 2019

main subject

1 reference

L Dupuis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

A Muller

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

V Meininger

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

J P Loeffler

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

publication date

1 January 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

volume

160

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

page(s)

35-43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis

24 November 2019

cites work

1 reference

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7 January 2021

Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid.

1 reference

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7 January 2021

Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

1 reference

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7 January 2021

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

1 reference

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7 January 2021

Blood oxidative stress in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superox

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Neuronal-specific expression of human copper-zinc superoxide dismutase gene in transgenic mice: animal model of gene dosage effects in Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Survival in transgenic ALS mice does not vary with CNS glutathione peroxidase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathological changes that most closely resemble those in human amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Differential screening of mutated SOD1 transgenic mice reveals early up-regulation of a fast axonal transport component in spinal cord motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Loss of prion protein in a transgenic model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Inhibition of ICE slows ALS in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Alteration of the Bcl-x/Bax ratio in a transgenic mouse model of amyotrophic lateral sclerosis: evidence for the implication of the p53 signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

A mouse model of familial amyotrophic lateral sclerosis expressing a mutant superoxide dismutase 1 shows evidence of disordered transport in the vasopressin hypothalamo-neurohypophysial axis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

The antioxidant N-acetylcysteine does not delay disease onset and death in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Effects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary results.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Early and selective pathology of light chain neurofilament in the spinal cord and sciatic nerve of G86R mutant superoxide dismutase transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Familial adult motor neuron disease: amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in G86R superoxide dismutase transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Minocycline delays disease onset and mortality in a transgenic model of ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Survival in patients with amyotrophic lateral sclerosis, treated with an array of antioxidants.

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0035-3787%2804%2970845-0

7 January 2021

10.1016/S0035-3787(04)70845-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978392%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference