(Q7671094)

p53/RUNT-type transcription factor, DNA-binding domain superfamily

1 reference

p53-like tetramerisation domain superfamily

1 reference

Tumour protein p63

1 reference

Sterile alpha motif/pointed domain superfamily

1 reference

Tumour protein p63, SAM domain, protein family

1 reference

Sterile alpha motif domain, protein family

1 reference

p53, tetramerisation domain, protein family

1 reference

p53, DNA-binding domain, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

9 references

8 April 2019

ASPP1 and ASPP2: common activators of p53 family members

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

PKCδ stabilizes TAp63 to promote cell apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Identification of DeltaNp63alpha protein interactions by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

The E3 ubiquitin ligase Itch controls the protein stability of p63

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

4 references

8 April 2019

A new human p53 homologue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

identical protein binding

5 references

8 April 2019

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Structural evolution of p53, p63, and p73: Implication for heterotetramer formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

5 June 2018

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

Functional interplay between MDM2, p63/p73 and mutant p53

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

DNA-binding transcription factor activity

IPI

MDM2/MDM4 family protein binding

1 reference

8 April 2019

Functional interplay between MDM2, p63/p73 and mutant p53

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

DNA-binding transcription factor activity, RNA polymerase II-specific

IPI

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

protein domain specific binding

ISA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

double-stranded DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

Expression of the p53 homologue p63alpha and deltaNp63alpha in normal and neoplastic cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

7 references

8 April 2019

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Expression of the p53 homologue p63alpha and deltaNp63alpha in normal and neoplastic cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

p63 is a prostate basal cell marker and is required for prostate development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

rough endoplasmic reticulum

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

transcription regulator complex

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

pattern specification process

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

skeletal system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

epithelial cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

negative regulation of keratinocyte differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

epidermal cell division

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

anatomical structure formation involved in morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

prostate gland development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

transcription by RNA polymerase II

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

squamous basal epithelial stem cell differentiation involved in prostate gland acinus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

ectoderm and mesoderm interaction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

cellular response to DNA damage stimulus

1 reference

5 June 2018

Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

female genitalia morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

odontogenesis of dentin-containing tooth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

prostatic bud formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

positive regulation of cell cycle G1/S phase transition

1 reference

5 June 2018

Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

positive regulation of mesenchymal cell proliferation

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

multicellular organism aging

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

smooth muscle tissue development

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

positive regulation of fibroblast apoptotic process

1 reference

8 April 2019

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

animal organ morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

hair follicle morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

regulation of neuron apoptotic process

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

positive regulation of apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

regulation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

embryonic limb morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

negative regulation of mesoderm development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

epidermis development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

post-anal tail morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

response to gamma radiation

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

protein homotetramerization

1 reference

8 April 2019

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

IPI

Notch signaling pathway

1 reference

8 April 2019

hair follicle development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

neuron apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

polarized epithelial cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

proximal/distal pattern formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

positive regulation of keratinocyte proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

epithelial cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

urinary bladder development

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

cellular response to UV

1 reference

5 June 2018

establishment of planar polarity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

protein tetramerization

1 reference

8 April 2019

keratinocyte proliferation

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

positive regulation of osteoblast differentiation

1 reference

8 April 2019

Hepatocyte growth factor (HGF) and 1,25-dihydroxyvitamin D together stimulate human bone marrow-derived stem cells toward the osteogenic phenotype by HGF-induced up-regulation of VDR

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

negative regulation of cellular senescence

1 reference

5 June 2018

Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

sympathetic nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

morphogenesis of a polarized epithelium

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

keratinocyte differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

mitotic G1 DNA damage checkpoint signaling

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4

positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

regulation of signal transduction by p53 class mediator

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

regulation of apoptotic process

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

negative regulation of intracellular estrogen receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

positive regulation of transcription, DNA-templated

4 references

8 April 2019

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Functional interplay between MDM2, p63/p73 and mutant p53

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

A novel response element confers p63- and p73-specific activation of the WNT4 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

8 April 2019

Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

positive regulation of somatic stem cell population maintenance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

epidermal cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

embryonic forelimb morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

embryonic hindlimb morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

skin epidermis development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

cranial skeletal system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

developmental process

1 reference

8 April 2019

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4

imported from Wikimedia project

Gene Atlas image

PBB GE TP73L 209863 s at tn.png
255 × 135; 543 bytes

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English Wikipedia

Identifiers

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13 November 2019

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9 August 2016

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