(Q54588191)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21602882%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage (English)

1 reference

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1 February 2020

0 references

8

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1 February 2020

Cinzia Rinaldo

4

1 reference

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1 February 2020

Armando Bartolazzi

7

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1 February 2020

Silvia Soddu

11

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1 February 2020

author name string

C Lazzari

1

1 reference

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1 February 2020

A Prodosmo

2

1 reference

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1 February 2020

F Siepi

3

1 reference

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1 February 2020

F Galli

5

1 reference

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1 February 2020

M Gentileschi

6

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1 February 2020

A Sacchi

9

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1 February 2020

L Guerrini

10

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1 February 2020

language of work or name

English

0 references

publication date

23 May 2011

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1 February 2020

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1 February 2020

volume

30

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21602882%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

4802-4813

1 reference

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1 February 2020

issue

48

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https://scigraph.springernature.com/pub.10.1038/onc.2011.182

1 February 2020

exact match

0 references

cites work

IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Negative regulation of beta4 integrin transcription by homeodomain-interacting protein kinase 2 and p53 impairs tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

From top to bottom: the two faces of HIPK2 for regulation of the hypoxic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

HIPK2: a versatile switchboard regulating the transcription machinery and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

p63 regulates an adhesion programme and cell survival in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

AIS is an oncogene amplified in squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Axin determines cell fate by controlling the p53 activation threshold after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

DeltaNp63 protein expression in uterine cervical and endometrial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Phosphorylation and stabilization of TAp63gamma by IkappaB kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

One, two, three--p53, p63, p73 and chemosensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Association of p63 with proliferative potential in normal and neoplastic human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

HIPK2: a multitalented partner for transcription factors in DNA damage response and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

The E3 ubiquitin ligase Itch controls the protein stability of p63

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Transcriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Delta Np73L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Therapeutic prospects for p73 and p63: rising from the shadow of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Cables1 protects p63 from proteasomal degradation to ensure deletion of cells after genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Roscovitine-activated HIP2 kinase induces phosphorylation of wt p53 at Ser-46 in human MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Ultraviolet radiation induces phosphorylation and ubiquitin-mediated degradation of DeltaNp63alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

DeltaNp63alpha levels correlate with clinical tumor response to cisplatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

Ser58 of mouse p53 is the homologue of human Ser46 and is phosphorylated by HIPK2 in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

The loss of the p53 activator HIPK2 is responsible for galectin-3 overexpression in well differentiated thyroid carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.182

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.182

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21602882%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference