(Q77370635)

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Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors

scientific article published on 01 February 1999

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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J T Eummer

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

B S Gibbs

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

T J Zahn

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

J S Sebolt-Leopold

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

R A Gibbs

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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1 February 1999

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Bioorganic & Medicinal Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

7

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

241-250

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Protein prenylation: molecular mechanisms and functional consequences

1 reference

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7 January 2021

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Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

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Ras farnesyltransferase: a new therapeutic target

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The potential of farnesyltransferase inhibitors as cancer chemotherapeutics

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Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

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Chemoprevention and therapy of cancer by d-limonene

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7 January 2021

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Growth inhibition of rat liver epithelial tumor cells by monoterpenes does not involve Ras plasma membrane association.

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Differential effects of monoterpenes and lovastatin on RAS processing

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Inhibition of tumor cell growth by monoterpenes in vitro: evidence of a Ras-independent mechanism of action.

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7 January 2021

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The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol

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7 January 2021

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Steady-state kinetic mechanism of Ras farnesyl:protein transferase

1 reference

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7 January 2021

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Structure-activity relationships among monoterpene inhibitors of protein isoprenylation and cell proliferation

1 reference

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7 January 2021

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Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity.

1 reference

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7 January 2021

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Design and synthesis of non-peptide Ras CAAX mimetics as potent farnesyltransferase inhibitors

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7 January 2021

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Phosphonate-containing inhibitors of tyrosine-specific protein kinases

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Inhibitors of farnesyl:protein transferase--a possible cancer chemotherapeutic

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7 January 2021

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Inhibition of type I and type II geranylgeranyl-protein transferases by the monoterpene perillyl alcohol in NIH3T3 cells

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7 January 2021

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Farnesyl diphosphate-based inhibitors of Ras farnesyl protein transferase

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7 January 2021

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Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents

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7 January 2021

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Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

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7 January 2021

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C-terminal modifications of histidyl-N-benzylglycinamides to give improved inhibition of Ras farnesyltransferase, cellular activity, and anticancer activity in mice

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7 January 2021

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A new class of highly potent farnesyl diphosphate-competitive inhibitors of farnesyltransferase

1 reference

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7 January 2021

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inferred from DOI database lookup

Differential prenyl pyrophosphate binding to mammalian protein geranylgeranyltransferase-I and protein farnesyltransferase and its consequence on the specificity of protein prenylation

1 reference

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7 January 2021

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Structure-activity relationships of cysteine-lacking pentapeptide derivatives that inhibit ras farnesyltransferase.

1 reference

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7 January 2021

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Stereochemistry-dependent inhibition of RAS farnesylation by farnesyl phosphonic acids

1 reference

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7 January 2021

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Identifiers

10.1016/S0968-0896(98)00202-8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10218815%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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