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Current issues in the enzymology of mitomycin C metabolic activation
scientific article published on 01 October 1998
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Current issues in the enzymology of mitomycin C metabolic activation
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
author name string
V J Spanswick
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
J Cummings
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
J F Smyth
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
publication date
1 October 1998
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
published in
General Pharmacology
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
volume
31
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
page(s)
539-544
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
cites work
Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bioactivation of mitomycin antibiotics by aerobic and hypoxic Chinese hamster ovary cells overexpressing DT-diaphorase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Encapsulation of mitomycin C in albumin microspheres markedly alters pharmacokinetics, drug quinone reduction in tumour tissue and antitumour activity. Implications for the drugs' in vivo mechanism of action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Re-evaluation of the molecular pharmacology of mitomycin C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reductive activation of mitomycin C: a delicate balance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of pH in murine tumor and muscle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reductive activation of mitomycin C
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycyclic aromatic hydrocarbon quinone-mediated oxidation reduction cycling catalyzed by a human placental NADPH-linked carbonyl reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-enzymatic and enzymatic activation of mitomycin C: identification of a unique cytosolic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolic activation of mitomycin C by liver microsomes and nuclei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DT-diaphorase as a quinone reductase: a cellular control device against semiquinone and superoxide radical formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on the mechanism of resistance to mitomycin C and porfiromycin in a human cell strain derived from a cancer-prone individual
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxic fractions of solid tumors: experimental techniques, methods of analysis, and a survey of existing data
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autocatalytic quinone methide formation from mitomycin c.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unusually marked hypoxic sensitization to indoloquinone EO9 and mitomycin C in a human colon-tumour cell line that lacks DT-diaphorase activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DT-diaphorase protects cells from the hypoxic cytotoxicity of indoloquinone EO9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolism and reactions of quinoid anticancer agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Re: Reductase enzyme expression across the National Cancer Institute tumor cell line panel: correlation with sensitivity to mitomycin C and E09
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of mitomycin C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytosolic NAD(P)H:(quinone-acceptor)oxidoreductase in human normal and tumor tissue: effects of cigarette smoking and alcohol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bioreductive activation of mitomycin C by DT-diaphorase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enzymology of mitomycin C metabolic activation in tumour tissue. Characterization of a novel mitochondrial reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction of oxygen by NADH/NADH dehydrogenase in the presence of adriamycin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reductive metabolism and alkylating activity of mitomycin C induced by rat liver microsomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DT-diaphorase activity correlates with sensitivity to the indoloquinone EO9 in mouse and human colon carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Occurrence and tissue distribution of both NADH- and NADPH-linked aquacobalamin reductases in some vertebrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NADPH-cytochrome c (P-450) reductase has the activity of NADPH-linked aquacobalamin reductase in rat liver microsomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Carbonyl reductase provides the enzymatic basis of quinone detoxication in man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exploiting tumor hypoxia through bioreductive release of diffusible cytotoxins: the cobalt(III)-nitrogen mustard complex SN 24771
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DT-diaphorase: questionable role in mitomycin C resistance, but a target for novel bioreductive drugs?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2898%2900055-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0306-3623(98)00055-X
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
PubMed ID
9792212
1 reference
stated in
Europe PubMed Central
PubMed ID
9792212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
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