(Q77725647)

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Methapyrilene hepatotoxicity is associated with oxidative stress, mitochondrial disfunction and is prevented by the Ca2+ channel blocker verapamil

scientific article published on 01 September 1998

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Europe PubMed Central

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7 December 2019

Methapyrilene hepatotoxicity is associated with oxidative stress, mitochondrial disfunction and is prevented by the Ca2+ channel blocker verapamil (English)

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Europe PubMed Central

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7 December 2019

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Winston A Morgan

2

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7 December 2019

Matthew C. Wright

5

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7 December 2019

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G S Ratra

1

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7 December 2019

J Mullervy

3

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7 December 2019

C J Powell

4

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7 December 2019

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1 September 1998

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7 December 2019

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Europe PubMed Central

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7 December 2019

130

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7 December 2019

2-3

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7 December 2019

79-93

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7 December 2019

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Studies with verapamil and nifedipine provide evidence for the presence in the liver cell plasma membrane of two types of Ca2+ inflow transporter which are dissimilar to potential-operated Ca2+ channels

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Metabolism of methapyrilene by rat-liver homogenate

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The in vivo metabolism of methapyrilene, a hepatocarcinogen, in the rat

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Cyclosporin A protects hepatocytes against prooxidant-induced cell killing. A study on the role of mitochondrial Ca2+ cycling in cytotoxicity

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Species differences in the metabolism and macromolecular binding of methapyrilene: a comparison of rat, mouse and hamster

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The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system

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Identifiers

10.1016/S0300-483X(98)00096-1

1 reference

Europe PubMed Central

PubMed publication ID

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7 December 2019

PubMed publication ID

1 reference

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PubMed publication ID

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7 December 2019

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