(Q77845951)

English

Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway

scientific article published on 01 May 1999

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scholarly article

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Europe PubMed Central

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8 December 2019

Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway (English)

1 reference

Europe PubMed Central

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8 December 2019

author name string

Rousseau D

1

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8 December 2019

Cannella D

2

1 reference

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8 December 2019

Boulaire J

3

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8 December 2019

Fitzgerald P

4

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8 December 2019

Fotedar A

5

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8 December 2019

Fotedar R

6

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8 December 2019

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1 May 1999

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8 December 2019

1 reference

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8 December 2019

18

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8 December 2019

3290-3302

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8 December 2019

21

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8 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202681

0 references

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

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Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

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p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

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Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein

1 reference

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7 January 2021

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Nuclear targeting sequences--a consensus?

1 reference

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7 January 2021

based on heuristic

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WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

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Cdk inhibitors: on the threshold of checkpoints and development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Role for cyclin A-dependent kinase in DNA replication in human S phase cell extracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation-induced T-cell death is cell cycle dependent and regulated by cyclin B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of p34cdc with Replicating DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of cyclin-dependent kinases by p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of wild-type and mutant p21WAF-1 gene activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Targets of cyclin-dependent protein kinases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleocytoplasmic transport: signals, mechanisms and regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclins, Cdks, and cyclin kinase inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis of cyclin-dependent kinase activation by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Proliferating cell nuclear antigen is required for DNA excision repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

p21 Disrupts the interaction between cdk2 and the E2F-p130 complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Smart machines at the DNA replication fork.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202681

7 January 2021

based on heuristic

inferred from DOI database lookup

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