(Q7798344)

Immunoglobulin-like fold

1 reference

Fibronectin type III, protein family

1 reference

based on heuristic

inferred from protein domain or family

Growth hormone/erythropoietin receptor, ligand binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Long hematopoietin receptor, single chain, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

cytokine receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

1 reference

8 April 2019

Mpl traffics to the cell surface through conventional and unconventional routes

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

transmembrane signaling receptor activity

IPI

1 reference

1 January 2018

Structure and transcription of the human c-mpl gene (MPL)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

thrombopoietin receptor activity

TAS

1 reference

8 April 2019

The thrombopoietin receptor P106L mutation functionally separates receptor signaling activity from thrombopoietin homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

integral component of membrane

IMP

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

8 April 2019

The thrombopoietin receptor P106L mutation functionally separates receptor signaling activity from thrombopoietin homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

integral component of plasma membrane

IDA

1 reference

1 January 2018

Structure and transcription of the human c-mpl gene (MPL)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

cell surface receptor signaling pathway

biological process

1 reference

1 January 2018

Structure and transcription of the human c-mpl gene (MPL)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

cell population proliferation

TAS

1 reference

1 January 2018

Structure and transcription of the human c-mpl gene (MPL)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

cytokine-mediated signaling pathway

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

thrombopoietin-mediated signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

neutrophil homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

positive regulation of lymphocyte proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

cellular response to hypoxia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

positive regulation of platelet formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

eosinophil homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40238

physically interacts with

romiplostim

object of statement has role

agonist

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201832

Gene Atlas image

PBB GE MPL 211903 s at fs.png
732 × 530; 12 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P40238

1 reference

Long hematopoietin receptor, single chain, conserved site

Identifiers.org

has part(s)

1 reference

fibronectin type III

1 reference

Growth hormone/erythropoietin receptor, ligand binding

1 reference

D12.776.543.750.705.852.610

Identifiers

MeSH descriptor ID

D053628

subject named as

Receptors, Thrombopoietin

0 references

MeSH tree code

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

inferred by common MeSH mappings on source and on Wikidata