(Q24311471)

thrombopoietin receptor activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

7

Niels H Gehring

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Andreas E Kulozik

8

object named as

Andreas E Kulozik

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author name string

Clemens Stockklausner

1

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Anne-Christine Klotter

2

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Nicole Dickemann

3

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Isabelle N Kuhlee

4

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Christin M Duffert

5

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Carolin Kerber

Genetic origins and clinical phenotype of familial and acquired erythrocytosis and thrombocytosis

6

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language of work or name

English

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publication date

12 February 2015

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published in

Blood

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volume

125

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issue

7

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page(s)

1159-69

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cites work

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

MPL mutations in 23 patients suffering from congenital amegakaryocytic thrombocytopenia: the type of mutation predicts the course of the disease

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Congenital amegakaryocytic thrombocytopenia: the diagnostic importance of combining pathology with molecular genetics

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

MPL W515L mutation in pediatric essential thrombocythemia.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Hereditary thrombocythemia caused by a thrombopoietin (THPO) gain-of-function mutation associated with multiple myeloma and congenital limb defects

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Detection of MPL exon10 mutations in 103 Chinese patients with JAK2V617F-negative myeloproliferative neoplasms

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Compound heterozygous c-Mpl mutations in a child with congenital amegakaryocytic thrombocytopenia: functional characterization and a review of the literature

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

F104S c-Mpl responds to a transmembrane domain-binding thrombopoietin receptor agonist: proof of concept that selected receptor mutations in congenital amegakaryocytic thrombocytopenia can be stimulated with alternative thrombopoietic agents

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Phosphorylated c-Mpl tyrosine 591 regulates thrombopoietin-induced signaling

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Orientation-specific signalling by thrombopoietin receptor dimers.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Hereditary thrombocythaemia in a Japanese family is caused by a novel point mutation in the thrombopoietin gene

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Mutations in the thrombopoietin receptor, Mpl, in children with congenital amegakaryocytic thrombocytopenia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Mpl Baltimore: a thrombopoietin receptor polymorphism associated with thrombocytosis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Ligand-independent thrombopoietin mutant receptor requires cell surface localization for endogenous activity

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD).

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Thrombopoietin from beginning to end.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Familial thrombocytosis caused by the novel germ-line mutation p.Pro106Leu in the MPL gene

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Erythropoietin receptor activation by a ligand-induced conformation change

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Thrombopoietin and thrombopoietin mimetics in the treatment of thrombocytopenia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

A novel therapeutic approach for thrombocytopenia by minibody agonist of the thrombopoietin receptor

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

New thrombopoietic growth factors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Historical review: megakaryopoiesis and thrombopoiesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

The Asn505 mutation of the c-MPL gene, which causes familial essential thrombocythemia, induces autonomous homodimerization of the c-Mpl protein due to strong amino acid polarity

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Mpl and thrombocytosis: levels matter

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Hereditary thrombocytosis not as innocent as thought? Development into acute leukemia and myelofibrosis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

A novel splice donor mutation in the thrombopoietin gene leads to exon 2 skipping in a Filipino family with hereditary thrombocythemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Membrane localization is not required for Mpl function in normal hematopoietic cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Markers of myeloproliferative diseases in childhood polycythemia vera and essential thrombocythemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Thrombopoietin receptor activation, thrombopoietin mimetic drugs, and hereditary thrombocytosis: remarks on bone marrow fibrosis.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Evidence for a founder effect of the MPL-S505N mutation in eight Italian pedigrees with hereditary thrombocythemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Hereditary thrombocytosis caused by MPLSer505Asn is associated with a high thrombotic risk, splenomegaly and progression to bone marrow fibrosis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

Deep sequencing reveals double mutations in cis of MPL exon 10 in myeloproliferative neoplasms.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-07-587170

7 January 2021

10.1182/BLOOD-2014-07-587170

Identifiers

DOI

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Fatcat ID

release_sx7egem3cfglbpbyy5oixgzk5m

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sx7egem3cfglbpbyy5oixgzk5m

24 November 2022