(Q78036210)

English

Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential

scientific article published on 01 June 1999

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

drug interaction

0 references

drug metabolism

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

author name string

C Lu

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

J A Brent

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

C Pham

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

A Fackett

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

C E Ruegg

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

P M Silber

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

publication date

1 June 1999

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

Chemico-biological Interactions

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

121

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

17-35

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

Difficulties in using animal data to predict pharmacological response in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Species differences in carcinogenicity: the role of metabolism in human risk evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Extrapolation from animals to man: predictions, pitfalls and perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Cytochromes P450 and species differences in xenobiotic metabolism and activation of carcinogen

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

The human drug metabolizing cytochromes P450.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Comparative metabolism of SC-42867 and SC-51089, two PGE2 antagonists, in rat and human hepatocyte cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Optimization of cryopreservation procedures for rat and human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

The human hepatic cytochromes P450 involved in drug metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Effective cryopreservation and long-term storage of primary human hepatocytes with recovery of viability, differentiation, and replicative potential.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Preservation of the rate and profile of xenobiotic metabolism in rat hepatocytes stored in liquid nitrogen

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Effect of cold and warm ischaemia on drug metabolism in isolated hepatocytes and slices from human and monkey liver.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Influence of 48 hours of cold storage in University of Wisconsin organ preservation solution on metabolic capacity of rat hepatocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Metabolic activity of fresh and cryopreserved dog hepatocyte suspensions.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Preparation and properties of primary maintenance cultures of adult rabbit hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

High-throughput approaches for evaluating absorption, distribution, metabolism and excretion properties of lead compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Evaluation of drug interactions in intact hepatocytes: Inhibitors of terfenadine metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900088-5

7 January 2021

Identifiers

10.1016/S0009-2797(99)00088-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10418968%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q78036210&oldid=2164974602"