(Q78067534)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

title

Radiation-induced genetic instability in vivo depends on p53 status (English)

1 reference

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10 December 2019

2

1 reference

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10 December 2019

Jay A. Tischfield

series ordinal

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

5

Peter J Stambrook

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

4

Marc S Mendonca

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

author name string

Li Liang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

Li Deng

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

language of work or name

English

0 references

publication date

1 May 2002

1 reference

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10 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

volume

502

1 reference

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10 December 2019

issue

1-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

page(s)

69-80

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

Clinical implications of the p53 tumor-suppressor gene

10 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Tumor spectrum analysis in p53-mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

p53 is required for radiation-induced apoptosis in mouse thymocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Thymocyte apoptosis induced by p53-dependent and independent pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Growth factor modulation of p53-mediated growth arrest versus apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

The dual role model for p53 in maintaining genomic integrity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

p53 deficiency does not affect the accumulation of point mutations in a transgene target

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

p53, mutation frequency and apoptosis in the murine small intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

APRT: a versatile in vivo resident reporter of local mutation and loss of heterozygosity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Chromosome instability contributes to loss of heterozygosity in mice lacking p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Real time quantitative PCR

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Mutants of cultured chinese hamster cells deficient in adenine phosphoribosyl transferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Genetic instability at the adenine phosphoribosyltransferase locus in mouse L cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Mutations causing deficiency of APRT in fibroblasts cultured from human heterozygous for mutant APRT alleles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Determination of spontaneous loss of heterozygosity mutations in Aprt heterozygous mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Targeted breakage of paracentromeric heterochromatin induces chromosomal instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Mutagenicity and loss of heterozygosity at the APRT locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

The Comparative Radiosensitivity of T and B Lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Radiation-induced genomic instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Interrelationships between radiation-induced mutations and modifications in gene expression linked to cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Genomic instability induced by ionizing radiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Carcinogen-induced loss of heterozygosity at the Aprt locus in somatic cells of the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Could p53 be a target for therapeutic suppression?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

p53-dependent apoptosis suppresses radiation-induced teratogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

The mutagenic potential of DNA double-strand break repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Requirement for p53 in ionizing-radiation-inhibition of double-strand-break rejoining by human lymphoblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900029-5

10.1016/S0027-5107(02)00029-5

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11996974%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

1 reference