(Q78108659)

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A perspective on the potential problems with aspirin as an antithrombotic agent: a comparison of studies in an animal model with clinical trials

scientific article published on 01 February 1999

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11 December 2019

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A perspective on the potential problems with aspirin as an antithrombotic agent: a comparison of studies in an animal model with clinical trials (English)

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11 December 2019

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James E. Muller

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J E Muller

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11 December 2019

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J D Folts

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11 December 2019

A I Schafer

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11 December 2019

J Loscalzo

3

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11 December 2019

J T Willerson

4

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11 December 2019

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1 February 1999

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11 December 2019

Journal of the American College of Cardiology

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Europe PubMed Central

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11 December 2019

33

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11 December 2019

2

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11 December 2019

295-303

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11 December 2019

Observations on the morbid anatomy of coronary artery disease

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The frequency and significance of coronary arterial thrombi and other observations in fatal acute myocardial infarction

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Inhibition of adenosine diphosphate-induced secondary aggregation and other platelet functions by acetylsalicylic acid ingestion

1 reference

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Impaired platelet-connective-tissue reaction in man after aspirin ingestion

1 reference

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7 January 2021

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Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

1 reference

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7 January 2021

based on heuristic

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Aspirin selectively inhibits prostaglandin production in human platelets

1 reference

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A Randomized Controlled Trial of Acetyl Salicyclic Acid in the Secondary Prevention of Mortality from Myocardial Infarction

1 reference

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7 January 2021

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Platelet aggregation in partially obstructed vessels and its elimination with aspirin.

1 reference

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7 January 2021

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In vivo models of arterial thrombosis and thrombolysis.

1 reference

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7 January 2021

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Cyclic flow variations in a conscious dog model of coronary artery stenosis and endothelial injury correlate with acute ischemic heart disease syndromes in humans

1 reference

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7 January 2021

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inferred from DOI database lookup

Administration of wine and grape juice inhibits in vivo platelet activity and thrombosis in stenosed canine coronary arteries

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Blood flow reductions in stenosed canine coronary arteries: vasospasm or platelet aggregation?

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Frequency and severity of cyclic flow alternations and platelet aggregation predict the severity of neointimal proliferation following experimental coronary stenosis and endothelial injury

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

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inferred from DOI database lookup

Characterization of the relative thrombogenicity of atherosclerotic plaque components: Implications for consequences of plaque rupture

1 reference

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7 January 2021

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Lewis A. Conner Memorial Lecture. Mechanisms leading to myocardial infarction: insights from studies of vascular biology

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The clinical importance of acquired abnormalities of platelet function

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Technical considerations for platelet aggregation and related problems

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Collagen type III induced ex vivo thrombogenesis in humans. Role of platelets and leukocytes in deposition of fibrin

1 reference

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7 January 2021

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inferred from DOI database lookup

Spontaneous alterations in coronary blood flow velocity before and after coronary angioplasty in patients with severe angina

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclic flow variations after coronary angioplasty in humans: clinical and angiographic characteristics and elimination with 7E3 monoclonal antiplatelet antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Conversion from chronic to acute coronary artery disease: Speculation regarding mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Cooperative mediation by serotonin S2 and thromboxane A2/prostaglandin H2 receptor activation of cyclic flow variations in dogs with severe coronary artery stenoses

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of acute platelet thrombosis formation in stenosed canine coronary arteries by specific serotonin 5HT2 receptor antagonist ritanserin

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

ADP plays an important role in mediating platelet aggregation and cyclic flow variations in vivo in stenosed and endothelium-injured canine coronary arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Final report on the aspirin component of the ongoing Physicians' Health Study

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death.

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Circadian variation and triggers of onset of acute cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Circadian variation of acute myocardial infarction and the effect of low-dose aspirin in a randomized trial of physicians

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Aspirin as an antiplatelet drug

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Aspirin as a therapeutic agent in cardiovascular disease: a statement for healthcare professionals from the American Heart Association

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiplatelet therapy

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Epinephrine potentiation of in viw stimuli reverses aspirin inhibition of platelet thrombos formation in stenosed canine coronary arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of aspirin and epinephrine on experimentally induced thrombogenesis in dogs. A parallelism between in vivo and ex vivo thrombosis models

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Triggering of acute myocardial infarction onset by episodes of anger. Determinants of Myocardial Infarction Onset Study Investigators

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Increased shear stress overcomes the antithrombotic platelet inhibitory effect of aspirin in stenosed dog coronary arteries.

1 reference

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based on heuristic

inferred from DOI database lookup

Epinephrine and shear stress synergistically induce platelet aggregation via a mechanism that partially bypasses VWF-GP IB interactions

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Differential effect of aspirin on platelet aggregation in IDDM

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Two-year follow-up of aspirin responder and aspirin non responder. A pilot-study including 180 post-stroke patients

1 reference

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based on heuristic

inferred from DOI database lookup

Antithrombotic therapy for deep arterial injury by angioplasty. Efficacy of common platelet inhibition compared with thrombin inhibition in pigs

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of growth of thrombus on fresh mural thrombus. Targeting optimal therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Ticlopidine and antiplatelet therapy

1 reference

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7 January 2021

based on heuristic

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A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Intravenous nitroglycerin infusion inhibits cyclic blood flow responses caused by periodic platelet thrombus formation in stenosed canine coronary arteries

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Sodium nitroprusside, an endothelium-derived relaxing factor congener, increases platelet cyclic GMP levels and inhibits epinephrine-exacerbated in vivo platelet thrombus formation in stenosed canine coronary arteries

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Endothelium-derived relaxing factor modulates platelet aggregation in an in vivo model of recurrent platelet activation

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiplatelet effects of nitroglycerin in healthy subjects and in patients with stable angina pectoris

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Antithrombotic properties of transdermal nitroglycerin in stable angina pectoris

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of platelet aggregation by transdermal glyceryl trinitrate

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiplatelet and antithrombotic effects of organic nitrates

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential inhibition of platelet aggregation and calcium mobilization by nitroglycerin and stabilized nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The antiplatelet effects of organic nitrates and related nitroso compounds in vitro and in vivo and their relevance to cardiovascular disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of intravenous nitrates on mortality in acute myocardial infarction: an overview of the randomised trials

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of platelet activity by S-nitrosoglutathione during coronary angioplasty

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Oral verapamil inhibits platelet thrombus formation in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of platelet activity in vivo by amlodipine alone and combined with aspirin

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcium channel blockers in acute myocardial infarction and unstable angina: an overview

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomised trial of coronary intervention with antibody against platelet IIb/IIIa iritegrin for reduction of clinical restenosis: results at six months

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina. European Cooperative Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

New antiplatelet agents for acute coronary syndromes

1 reference

https://api.crossref.org/works/10.1016%2FS0735-1097%2898%2900601-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0735-1097(98)00601-9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9973006%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9973006%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

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