(Q78807324)

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Cell-permeable ceramides increase basal glucose incorporation into triacylglycerols but decrease the stimulation by insulin in 3T3-L1 adipocytes

scientific article published on 01 January 2003

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scholarly article

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Europe PubMed Central

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16 December 2019

Cell-permeable ceramides increase basal glucose incorporation into triacylglycerols but decrease the stimulation by insulin in 3T3-L1 adipocytes (English)

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Europe PubMed Central

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16 December 2019

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J Mei

1

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16 December 2019

C-N Wang

2

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16 December 2019

L O'Brien

3

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16 December 2019

D N Brindley

4

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16 December 2019

publication date

1 January 2003

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16 December 2019

27

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16 December 2019

1

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16 December 2019

31-39

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Europe PubMed Central

PubMed publication ID

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16 December 2019

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

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Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

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The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

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Tumor necrosis factor alpha inhibits signaling from the insulin receptor

1 reference

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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

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Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1

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The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling

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Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

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7 January 2021

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Ceramide inhibition of mammalian phospholipase D1 and D2 activities is antagonized by phosphatidylinositol 4,5-bisphosphate

1 reference

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7 January 2021

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The dimeric and catalytic subunit forms of protein phosphatase 2A from rat brain are stimulated by C2-ceramide

1 reference

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7 January 2021

based on heuristic

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Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase

1 reference

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7 January 2021

based on heuristic

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Sphingomyelinase and ceramide suppress insulin-induced tyrosine phosphorylation of the insulin receptor substrate-1

1 reference

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7 January 2021

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Effect of tumor necrosis factor-alpha on insulin action in cultured rat skeletal muscle cells

1 reference

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7 January 2021

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Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor.

1 reference

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7 January 2021

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Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction.

1 reference

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7 January 2021

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Effects of cell-permeable ceramides and tumor necrosis factor-alpha on insulin signaling and glucose uptake in 3T3-L1 adipocytes

1 reference

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7 January 2021

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A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

1 reference

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Tumor necrosis factor-alpha induces stress fiber formation through ceramide production: role of sphingosine kinase.

1 reference

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7 January 2021

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Tumor necrosis factor promotes phosphorylation and binding of insulin receptor substrate 1 to phosphatidylinositol 3-kinase in 3T3-L1 adipocytes

1 reference

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7 January 2021

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Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle

1 reference

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7 January 2021

based on heuristic

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Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802183

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802183

7 January 2021

based on heuristic

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Tumor necrosis factor-alpha regulation of glucose transporter (GLUT1) mRNA turnover. Contribution of the 3'-untranslated region of the GLUT1 message

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802183

7 January 2021

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Decreased incorporation of glucose into lipids and increased lactate production by adipose tissue after long-term treatment of rats with D-fenfluramine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802183

7 January 2021

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Decreased serum lipids, serum insulin and triacylglycerol synthesis in adipose tissue of JCR:LA-corpulent rats treated with benfluorex.

1 reference

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7 January 2021

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Differential sorting of two glucose transporters expressed in insulin-sensitive cells

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

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Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase

1 reference

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7 January 2021

based on heuristic

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Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

1 reference

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7 January 2021

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

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7 January 2021

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Insulin-induced phosphorylation and activation of phosphodiesterase 3B in rat adipocytes: possible role for protein kinase B but not mitogen-activated protein kinase or p70 S6 kinase

1 reference

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The insulin-dependent biosynthesis of GLUT1 and GLUT3 glucose transporters in L6 muscle cells is mediated by distinct pathways. Roles of p21ras and pp70 S6 kinase

1 reference

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

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1 reference

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Ceramide regulates lipopolysaccharide-induced phosphatidylinositol 3-kinase and Akt activity in human alveolar macrophages

1 reference

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The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

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Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

1 reference

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

1 reference

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

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based on heuristic

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Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

1 reference

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7 January 2021

based on heuristic

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Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802183

7 January 2021

based on heuristic

inferred from DOI database lookup

C(2)-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes

1 reference

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based on heuristic

inferred from DOI database lookup

Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-alpha on differentiation, insulin-stimulated glucose uptake, and gene expression in 3T3-L1 cells

1 reference

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Differential regulation of GLUT1 and GLUT4 glucose transporters in skeletal muscle of a new model of type II diabetes. The obese SHR/N-cp rat

1 reference

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Identifiers

10.1038/SJ.IJO.0802183

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12532151%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12532151%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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