(Q78862751)

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Fluid shear stress-induced transcriptional activation of the vascular endothelial growth factor receptor-2 gene requires Sp1-dependent DNA binding

scientific article published on 01 January 2003

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17 December 2019

Fluid shear stress-induced transcriptional activation of the vascular endothelial growth factor receptor-2 gene requires Sp1-dependent DNA binding (English)

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17 December 2019

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Carmen Urbich

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17 December 2019

Stefanie Dimmeler

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Stefanie Dimmeler

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17 December 2019

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Jens Gille

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17 December 2019

Kerstin Bianca Reisinger

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Kerstin Reisinger

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17 December 2019

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Monika Stein

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17 December 2019

Roland Kaufmann

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17 December 2019

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1 January 2003

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17 December 2019

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17 December 2019

535

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17 December 2019

1-3

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17 December 2019

87-93

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17 December 2019

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Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors

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Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

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Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

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7 January 2021

Regulation of vascular endothelial growth factor receptor-2 (Flk-1) expression in vascular endothelial cells.

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7 January 2021

Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (flk-1) are expressed during vasculogenesis and vascular differentiation in the quail embryo.

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7 January 2021

Downregulation of vascular endothelial growth factor receptors by tumor necrosis factor-alpha in cultured human vascular endothelial cells

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Transforming growth factor beta 1 down-regulates vascular endothelial growth factor receptor 2/flk-1 expression in vascular endothelial cells.

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7 January 2021

The role of mechanical stresses in microvascular remodeling

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Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis

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7 January 2021

The controls of microvascular survival

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Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells

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7 January 2021

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

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7 January 2021

Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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Nuclear protein interactions with the human KDR/flk-1 promoter in vivo. Regulation of Sp1 binding is associated with cell type-specific expression

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7 January 2021

Sequence-specific recognition of DNA by zinc-finger peptides derived from the transcription factor Sp1

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7 January 2021

Fractal characteristics of tumor vascular architecture during tumor growth and regression

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7 January 2021

Shear stress induces expression of vascular endothelial growth factor receptor Flk-1/KDR through the CT-rich Sp1 binding site

1 reference

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7 January 2021

Homologous up-regulation of KDR/Flk-1 receptor expression by vascular endothelial growth factor in vitro.

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7 January 2021

Transforming growth factor-beta 1-mediated inhibition of the flk-1/KDR gene is mediated by a 5'-untranslated region palindromic GATA site

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7 January 2021

Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequence

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7 January 2021

Induction of human vascular endothelial stress fibres by fluid shear stress

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Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation

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Shear stress induction of the tissue factor gene

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Identifiers

10.1016/S0014-5793(02)03879-6

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12560084%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12560084%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

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