(Q79194716)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17023504%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3 (English)

1 reference

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20 December 2019

1 reference

1 reference

4

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20 December 2019

author name string

Kate S Stokoe

1

1 reference

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20 December 2019

Glyn Thomas

2

1 reference

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20 December 2019

Catharine A Goddard

3

1 reference

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20 December 2019

Andrew A Grace

5

1 reference

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20 December 2019

Christopher L-H Huang

6

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20 December 2019

publication date

5 October 2006

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20 December 2019

published in

Journal of Physiology

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20 December 2019

volume

578

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20 December 2019

issue

Pt 1

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20 December 2019

page(s)

69-84

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Epicardial activation patterns of torsade de pointes in canine hearts with quinidine-induced long QT interval but without myocardial infarction

20 December 2019

cites work

1 reference

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Caffeine-induced arrhythmias in murine hearts parallel changes in cellular Ca(2+) homeostasis

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Delayed paced ventricular activation in the long QT syndrome is associated with ventricular fibrillation

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Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotes reentrant ventricular tachycardia

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Effects of flecainide in patients with new SCN5A mutation: mutation-specific therapy for long-QT syndrome?

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12 December 2020

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The Elusive Link Between LQT3 and Brugada Syndrome

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Normalization of ventricular repolarization with flecainide in long QT syndrome patients with SCN5A:DeltaKPQ mutation

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Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.

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Quinidine induced electrocardiographic normalization in two patients with Brugada syndrome

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Monophasic action potential recordings from intact mouse heart: validation, regional heterogeneity, and relation to refractoriness

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Brugada syndrome: why are there multiple answers to a simple question?

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Electrical heterogeneity within the ventricular wall

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12 December 2020

Inherited sodium channelopathies: models for acquired arrhythmias?

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12 December 2020

Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations

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12 December 2020

Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation

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12 December 2020

Microelectrode study of the genesis of the monophasic action potential by contact electrode technique

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12 December 2020

K+ channel structure-activity relationships and mechanisms of drug-induced QT prolongation.

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12 December 2020

Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice

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12 December 2020

Flecainide test in Brugada syndrome: a reproducible but risky tool.

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12 December 2020

Sudden Death in Noncoronary Heart Disease Is Associated With Delayed Paced Ventricular Activation

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12 December 2020

Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1

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12 December 2020

Does QT Widening in the Langendorff-perfused Rat Heart Represent the Effect of Repolarization Delay or Conduction Slowing?

1 reference

12 December 2020

Spatial dispersion of repolarization is a key factor in the arrhythmogenicity of long QT syndrome

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12 December 2020

Mechanisms for cardiac arrhythmias

1 reference

12 December 2020

Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current

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12 December 2020

Torsade de pointes induced by quinidine: a case treated successfully with verapamil

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12 December 2020

Sodium channel block produces opposite electrophysiological effects in canine ventricular epicardium and endocardium.

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12 December 2020

Torsades de pointes and ventricular fibrillation in a canine model of quinidine-induced QT prolongation

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12 December 2020

Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry?

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12 December 2020

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

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12 December 2020

Molecular mechanism for an inherited cardiac arrhythmia

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12 December 2020

Pharmacological targeting of long QT mutant sodium channels

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12 December 2020

Bipolar leads for use with permanently implantable cardiac pacing systems: a review of limitations of traditional and coaxial configurations and the development and testing of new conductor, insulation, and electrode designs

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12 December 2020

QT prolongation and development of torsades de pointes with the concomitant administration of oral erythromycin base and quinidine.

1 reference

12 December 2020

Genetically induced reduction in small currents has major impact

1 reference

12 December 2020

Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade des pointes in LQT2 and LQT3 models of the long-QT syndrome

1 reference

12 December 2020

Effects of sodium channel block with mexiletine to reverse action potential prolongation in in vitro models of the long term QT syndrome

1 reference

12 December 2020

Cellular basis for QT dispersion.

1 reference

12 December 2020

Influence of the genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group.

1 reference

12 December 2020

"Brugada" syndrome: clinical data and suggested pathophysiological mechanism

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12 December 2020

Cellular and ionic basis for T-wave alternans under long-QT conditions

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12 December 2020

Current status of monophasic action potential recording: theories, measurements and interpretations

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12 December 2020

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12 December 2020

QUINIDINE SYNCOPE. PAROXYSMAL VENTRICULAR FIBRILLATION OCCURRING DURING TREATMENT OF CHRONIC ATRIAL ARRHYTHMIAS.

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12 December 2020

Nifedipine and diltiazem suppress ventricular arrhythmogenesis and calcium release in mouse hearts

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12 December 2020

Transmural dispersion of repolarization as a key factor of arrhythmogenicity in a novel intact heart model of LQT3

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12 December 2020

Numerical simulation of paced electrogram fractionation: relating clinical observations to changes in fibrosis and action potential duration

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12 December 2020

Hydroquinidine therapy in Brugada syndrome

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12 December 2020

Efficacy of quinidine in high-risk patients with Brugada syndrome

1 reference

12 December 2020

State-dependent trapping of flecainide in the cardiac sodium channel

1 reference

12 December 2020

Torsade de pointes due to quinidine: observations in 31 patients

1 reference

12 December 2020

Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers. Relationship to potassium and cycle length.

1 reference

12 December 2020

Clinical features and basic mechanisms of quinidine-induced arrhythmias

1 reference

12 December 2020