(Q79222798)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

1 reference

S K Pinnamaneni

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

R J Southgate

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

M A Febbraio

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

M J Watt

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

publication date

11 October 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

3027-3037

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17033839%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00125-006-0427-9

20 December 2019

exact match

0 references

cites work

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

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12 December 2020

The metabolic syndrome

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12 December 2020

Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

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12 December 2020

Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B

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12 December 2020

Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

1 reference

12 December 2020

Skeletal muscle triglyceride levels are inversely related to insulin action.

1 reference

12 December 2020

Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans

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12 December 2020

Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans

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12 December 2020

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

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12 December 2020

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.

1 reference

12 December 2020

Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid

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12 December 2020

Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes

1 reference

12 December 2020

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

1 reference

12 December 2020

Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle

1 reference

12 December 2020

How obesity causes diabetes: not a tall tale

1 reference

12 December 2020

Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma

1 reference

12 December 2020

Mechanism of rat liver microsomal stearyl-CoA desaturase. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid

1 reference

12 December 2020

Hormone-sensitive lipase activity and triacylglycerol hydrolysis are decreased in rat soleus muscle by cyclopiazonic acid

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12 December 2020

Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding

1 reference

12 December 2020

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

12 December 2020

Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue

1 reference

12 December 2020

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

1 reference

12 December 2020

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

1 reference

12 December 2020

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1 reference

12 December 2020

Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle

1 reference

12 December 2020

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

1 reference

12 December 2020

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

1 reference

12 December 2020

Diet composition and insulin action in animal models

1 reference

12 December 2020

Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1.

1 reference

12 December 2020

Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes

1 reference

12 December 2020

Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.

1 reference

12 December 2020

DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells

1 reference

12 December 2020

Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cells

1 reference

12 December 2020

Human skeletal muscle fatty acid and glycerol metabolism during rest, exercise and recovery

1 reference

12 December 2020

Muscle triglyceride and insulin resistance

1 reference

12 December 2020

Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome

1 reference

12 December 2020

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

1 reference

12 December 2020

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

1 reference

12 December 2020

Differential effects of safflower oil versus fish oil feeding on insulin-stimulated glycogen synthesis, glycolysis, and pyruvate dehydrogenase flux in skeletal muscle: a 13C nuclear magnetic resonance study.

1 reference

12 December 2020

Gene expression profiling in skeletal muscle of Zucker diabetic fatty rats: implications for a role of stearoyl-CoA desaturase 1 in insulin resistance

1 reference

12 December 2020

Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis.

1 reference

12 December 2020

Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes

1 reference

12 December 2020

Regulation of stearoyl-CoA desaturases and role in metabolism

1 reference

12 December 2020

Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

1 reference

12 December 2020

Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment

1 reference

12 December 2020

Site and mechanism of leptin action in a rodent form of congenital lipodystrophy

1 reference

12 December 2020

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

1 reference

12 December 2020