(Q79753144)

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NT-3 and CNTF exert dose-dependent, pleiotropic effects on cells in the immature dorsal root ganglion: neuregulin-mediated proliferation of progenitor cells and neuronal differentiation

scientific article published on 19 May 2006

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25 December 2019

NT-3 and CNTF exert dose-dependent, pleiotropic effects on cells in the immature dorsal root ganglion: neuregulin-mediated proliferation of progenitor cells and neuronal differentiation (English)

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Sharon J Hapner

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Katherine M Nielsen

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Marta Chaverra

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Raymond M Esper

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Jeffrey A Loeb

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Frances Lefcort

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Developmental Biology

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25 December 2019

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trkC-mediated NT-3 signaling is required for the early development of a subpopulation of neurogenic neural crest cells.

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Schwann cells and their precursors emerge as major regulators of nerve development

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Inhibition of the NT-3 receptor TrkC, early in chick embryogenesis, results in severe reductions in multiple neuronal subpopulations in the dorsal root ganglia.

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Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila

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Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice.

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