(Q79938831)

English

Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs

scientific article published on 01 April 2007

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scholarly article

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27 December 2019

Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17358024%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Elaine J Abrams

8

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Elaine J Abrams

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27 December 2019

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Roberta B Ness

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27 December 2019

Vernon E Walker

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Vernon E Walker

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27 December 2019

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Dale M Walker

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27 December 2019

Miriam C. Poirier

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Miriam C Poirier

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27 December 2019

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Ofelia A Olivero

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27 December 2019

1

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Quanxin Meng

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27 December 2019

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Nancy A Wade

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27 December 2019

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Carol J Nesel

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27 December 2019

William L Bigbee

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William L Bigbee

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27 December 2019

author name string

Michael J Fasco

3

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27 December 2019

Ronald Bellisario

4

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27 December 2019

Laurence Kaminsky

5

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27 December 2019

Ken A Pass

6

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27 December 2019

J Patrick O'Neill

12

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27 December 2019

publication date

1 April 2007

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27 December 2019

Environmental and Molecular Mutagenesis

1 reference

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27 December 2019

48

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27 December 2019

3-4

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27 December 2019

307-321

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27 December 2019

Clinical pharmacokinetics of zidovudine. An update

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

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Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical pharmacology of zidovudine in human T-lymphoblastoid cells (CEM).

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Zidovudine phosphorylation in HIV-infected patients and seronegative volunteers

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Zidovudine: a review of its use in the management of vertically-acquired pediatric HIV infection

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

A pilot study of low-dose zidovudine in human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

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The metabolism of zidovudine by human liver microsomes in vitro: formation of 3'-amino-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

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Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene mutations with characteristic deletions in cord blood T lymphocytes associated with passive maternal exposure to tobacco smoke

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

A randomized controlled trial of a reduced daily dose of zidovudine in patients with the acquired immunodeficiency syndrome. The AIDS Clinical Trials Group

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Concentration-controlled zidovudine therapy

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Correlation between intracellular pharmacological activation of nucleoside analogues and HIV suppression in vitro

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

A method for the quantification of intracellular zidovudine nucleotides

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

The bottleneck in AZT activation

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo hprt mutant frequencies in T-cells of normal human newborns

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutagenicity and loss of heterozygosity at the APRT locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

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Successes and Challenges in the Perinatal HIV-1 Epidemic in the United States as Illustrated by the HIV-1 Serosurvey of Childbearing Women

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Incorporation of zidovudine into cord blood DNA of infants and peripheral blood DNA of their HIV-1-positive mothers

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular phosphorylation of zidovudine (ZDV) and other nucleoside reverse transcriptase inhibitors (RTI) used for human immunodeficiency virus (HIV) infection

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantification of zidovudine and individual zidovudine phosphates in peripheral blood mononuclear cells by a combined isocratic high performance liquid chromatography radioimmunoassay method

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Incorporation of 3'-azido-3'-deoxythymidine (AZT) into fetal DNA and fetal tissue distribution of drug after infusion of pregnant late-term rhesus macaques with a human-equivalent AZT dose

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucuronidation of 3'-azido-3'-deoxythymidine: human and rat enzyme specificity

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Enzymatic assay for measurement of zidovudine triphosphate in peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitation of intracellular zidovudine phosphates by use of combined cartridge-radioimmunoassay methodology.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

A systemic and cellular model for zidovudine plasma concentrations and intracellular phosphorylation in patients

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Zidovudine response relationships in early human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative analysis of 3'-azido-3'-deoxythymidine incorporation into DNA in human colon tumor cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

The triple combination indinavir-zidovudine-lamivudine is highly synergistic

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of nucleoside analog antiretrovirals: a review for clinicians

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

The stability of intracellular zidovudine and its anabolites in extracts of peripheral blood mononuclear cells (PBMCs).

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular metabolism of 3'-azidothymidine in isolated human peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Treating HIV during pregnancy: an update on safety issues

1 reference

https://api.crossref.org/works/10.1002%2FEM.20298

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EM.20298

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17358024%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17358024%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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