(Q79957787)

English

Polymorphisms of interleukin (IL)-4 receptor alpha and signal transducer and activator of transcription-6 (Stat6) are associated with increased IL-4Ralpha-Stat6 signalling in lymphocytes and elevated serum IgE in patients with Graves' disease

scientific article published on 15 March 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Polymorphisms of interleukin (IL)-4 receptor alpha and signal transducer and activator of transcription-6 (Stat6) are associated with increased IL-4Ralpha-Stat6 signalling in lymphocytes and elevated serum IgE in patients with Graves' disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Graves' disease

1 reference

based on heuristic

inferred from title

author name string

K Yabiku

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

M Hayashi

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

I Komiya

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

T Yamada

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Y Kinjo

5

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Europe PubMed Central

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27 December 2019

Y Ohshiro

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

T Kouki

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

N Takasu

8

1 reference

Europe PubMed Central

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27 December 2019

publication date

15 March 2007

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Europe PubMed Central

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27 December 2019

Clinical and Experimental Immunology

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

148

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

3

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Europe PubMed Central

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27 December 2019

425-431

1 reference

Europe PubMed Central

PubMed publication ID

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27 December 2019

No association between atopy/asthma and the ILe50Val polymorphism of IL-4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a functional repeat polymorphism in the promoter of the human NRAMP1 gene that correlates with autoimmune versus infectious disease susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of high affinity receptors for murine interleukin 4 (BSF-1) on hemopoietic and nonhemopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of asthma with serum IgE levels and skin-test reactivity to allergens

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between Airway Responsiveness and Serum IgE in Children with Asthma and in Apparently Normal Children

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of Tyrosine Phosphorylation for Rapid Activation of a DNA Binding Factor by IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human IgE network

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-gamma activation site-like sequence upstream of the I epsilon exon in a human B cell line. Evidence for the involvement of J

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 induces human B cell maturation and IgE synthesis in SCID-hu mice. Inhibition of ongoing IgE production by in vivo treatment with an IL-4/IL-13 receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of Stat6 in IL-4 signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization and functional analysis of murine interleukin 4 receptor allotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-13 receptor alpha' but not alpha chain: a functional component of interleukin-4 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A promoter-associated polymorphic repeat modulates PAX-6 expression in human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the human stat6 gene to chromosome 12q13.3-q14.1, a region implicated in multiple solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for IL-13 independently of IL-4 in experimental asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the interleukin-4 receptor alpha variant Q576R with Th1/Th2 imbalance in connective tissue disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An elevation of serum immunoglobulin E provides a new aspect of hyperthyroid Graves' disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel polymorphism in the 5' promoter region of the human interleukin-4 receptor alpha-chain gene is associated with decreased soluble interleukin-4 receptor protein levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remission and recurrence of hyperthyroid Graves' disease during and after methimazole treatment when assessed by IgE and interleukin 13.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel dinucleotide repeat polymorphism in the first exon of the STAT-6 gene is associated with allergic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation in dinucleotide (GT) repeat sequence in the first exon of the STAT6 gene is associated with atopic asthma and differentially regulates the promoter activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of Long-Acting Thyroid Stimulator (LATS) by Anti-kappa and Anti-lambda Antisera1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: dominant effect of Ile50Val variant of the human IL-4 receptor alpha-chain in IgE synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of epidermal growth factor receptor gene transcription by a polymorphic dinucleotide repeat in intron 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A possible role of immunoglobulin E in patients with hyperthyroid Graves' disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17362266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2249.2007.03366.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17362266%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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