(Q80017387)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17379368%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

An evaluation of the sensitivity of the Ames assay to discern low-level mutagenic impurities (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17379368%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Michelle O Kenyon

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17379368%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Jennifer R Cheung

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17379368%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Krista L Dobo

3

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27 December 2019

Warren W Ku

4

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27 December 2019

publication date

4 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17379368%20AND%20SRC:MED&resulttype=core&format=json

Regulatory Toxicology and Pharmacology

27 December 2019

published in

1 reference

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27 December 2019

volume

48

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27 December 2019

issue

1

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27 December 2019

page(s)

75-86

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17379368%20AND%20SRC:MED&resulttype=core&format=json

Potent mutagenicity to Salmonella of an equimolar mixture of 52 chemicals used in five collaborative studies.

27 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Near-total reduction in verapamil bioavailability by rifampin. Electrocardiographic correlates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Impurities in drug substances and drug products: new approaches to quantification and qualification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Use of the Miniscreen assay to screen novel compounds for bacterial mutagenicity in the pharmaceutical industry.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

7 January 2021

Is mannitol metabolized?

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Modulation of the potency of promutagens and direct acting mutagens in bacteria by inhibitors of the multidrug resistance mechanism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Spiral Salmonella assay: validation against the standard pour-plate assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Comparison of the results of a modified miniscreen and the standard bacterial reverse mutation assays.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Bioassay-directed chemical analysis and detection of mutagenicity in ambient air of the coke oven.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Mutagenicity and toxicity of aflatoxin precursors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Mutagenicity study of Remsen-Fahlberg saccharin and contaminants.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Mini mutagenicity test: a miniaturized version of the Ames test used in a prescreening assay for point mutagenesis assessment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Knowledge-based expert systems for toxicity and metabolism prediction: DEREK, StAR and METEOR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Advantage of the use of human liver S9 in the Ames test

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Use of human liver S9 in the Ames test: assay of three procarcinogens using human S9 derived from multiple donors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Detection of oxidative mutagens in an urban air-particulate extract: a preliminary study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Towards the creation of an international toxicology information centre.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

The Salmonella typhimurium/mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Identification of P450 enzymes involved in metabolism of verapamil in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Chemical purity and mutagenicity: case study of a drug in development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Qualitative and quantitative procedures for health risk assessment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

International Commission for Protection Against Environmental Mutagens and Carcinogens. A method for comparing and combining short-term genotoxicity test data: the basic system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Bacterial and mammalian-cell genotoxicity of mixtures of chlorohydroxyfuranones, by-products of water chlorination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Inhibition of hepatic microsomal drug metabolism in rats by five calcium antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Revised methods for the Salmonella mutagenicity test

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Determination of hydrazine in pharmaceuticals III: hydralazine and isoniazid using GLC

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Computer prediction of possible toxic action from chemical structure: an update on the DEREK system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Characterization of impurities in commercial lots of sodium saccharin produced by the Sherwin-Williams process. II. Mutagenicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Computer Prediction of Possible Toxic Action from Chemical Structure; The DEREK System

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Genotoxic and mutagenic activation of aflatoxin B1 by constitutive forms of cytochrome P-450 in rat liver microsomes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Evaluation of the genotoxicity of process stream extracts from a coal gasification system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

The Genetic Activity Profile database

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

A comparison of aflatoxin B1-induced cytotoxicity, mutagenicity and prophage induction in Salmonella typhimurium mutagen tester strains TA1535, TA1538, TA98 and TA100.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2007.01.006

10.1016/J.YRTPH.2007.01.006

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17379368%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference