(Q80263042)

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N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model

scientific article published on 04 August 2006

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30 December 2019

N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model (English)

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30 December 2019

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Wim Jiskoot

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30 December 2019

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Maryam Amidi

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Stefan G Romeijn

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30 December 2019

J Coos Verhoef

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30 December 2019

Hans E Junginger

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30 December 2019

Laura Bungener

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30 December 2019

Daan J A Crommelin

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4 August 2006

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30 December 2019

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30 December 2019

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30 December 2019

IgG2a restriction of murine antibodies elicited by viral infections

1 reference

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The IgG subclass responses to influenza virus haemagglutinin in the mouse: effect of route of inoculation

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7 January 2021

Influenza virus neutralizing antibodies and IgG isotype profiles after immunization of mice with influenza A subunit vaccine using various adjuvants

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Mutant Escherichia coli heat-labile enterotoxin [LT(R192G)] enhances protective humoral and cellular immune responses to orally administered inactivated influenza vaccine

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7 January 2021

Immunity to influenza in man

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7 January 2021

Cross-protection in mice infected with influenza A virus by the respiratory route is correlated with local IgA antibody rather than serum antibody or cytotoxic T cell reactivity

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7 January 2021

Comparison of Serology and Reactogenicity between Influenza Subunit Vaccines and Whole Virus or Split Vaccines: A Review and Meta-Analysis of the Literature

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7 January 2021

Nasal delivery of vaccines

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7 January 2021

Chitosan as a novel nasal delivery system for vaccines

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7 January 2021

The role of nasopharyngeal lymphoid tissue

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7 January 2021

NALT- versus Peyer's-patch-mediated mucosal immunity

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7 January 2021

Evaluation of the clearance characteristics of bioadhesive systems in humans

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7 January 2021

Clearance characteristics of chitosan based formulations in the sheep nasal cavity

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7 January 2021

Nasal drug delivery--possibilities, problems and solutions

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7 January 2021

A novel bioadhesive intranasal delivery system for inactivated influenza vaccines

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7 January 2021

Generation of Toxoplasma gondii GRA1 protein and DNA vaccine loaded chitosan particles: preparation, characterization, and preliminary in vivo studies

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7 January 2021

Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice

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7 January 2021

Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice

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7 January 2021

Potential of polymer microencapsulation technology for vaccine innovation

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7 January 2021

Aspects of the design and delivery of microparticles for vaccine applications

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Single dose, polymeric, microparticle-based vaccines: the influence of formulation conditions on the magnitude and duration of the immune response to a protein antigen

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7 January 2021

Potential of polymeric lamellar substrate particles (PLSP) as adjuvants for vaccines

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7 January 2021

Chitosan and its use as a pharmaceutical excipient

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7 January 2021

Chitosan: a unique polysaccharide for drug delivery.

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7 January 2021

Chitosan as a novel nasal delivery system for peptide drugs

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7 January 2021

Blood compatibility and biodegradability of partially N-acylated chitosan derivatives

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Human enzymatic activities related to the therapeutic administration of chitin derivatives

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Chitosan--as a biomaterial

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7 January 2021

Chitosan for enhanced intestinal permeability: prospects for derivatives soluble in neutral and basic environments

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7 January 2021

N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces: in vitro evaluation in intestinal epithelial cells (Caco-2).

1 reference

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7 January 2021

Intestinal absorption of octreotide: N-trimethyl chitosan chloride (TMC) ameliorates the permeability and absorption properties of the somatostatin analogue in vitro and in vivo.

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7 January 2021

Effect of the degree of quaternisation of N-trimethyl chitosan chloride on absorption enhancement: in vivo evaluation in rat nasal epithelia

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Modulation of immune response to group C meningococcal conjugate vaccine given intranasally to mice together with the LTK63 mucosal adjuvant and the trimethyl chitosan delivery system

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7 January 2021

Large molecule and particulate uptake in the nasal cavity: the effect of size on nasal absorption

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7 January 2021

Transport of nanoparticles across the rat nasal mucosa.

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7 January 2021

Immune response to nasal delivery of antigenically intact tetanus toxoid associated with poly(L-lactic acid) microspheres in rats, rabbits and guinea-pigs

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7 January 2021

Microsphere absorption by the nasal mucosa of the rat

1 reference

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7 January 2021

Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system

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Mucosal immunoadjuvant activity of recombinant Escherichia coli heat-labile enterotoxin and its B subunit: induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with influenza virus surface antigen

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7 January 2021

Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgG-mediated protective mucosal immunity

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Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration

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7 January 2021

The concomitant use of the LTK63 mucosal adjuvant and of chitosan-based delivery system enhances the immunogenicity and efficacy of intranasally administered vaccines.

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Lung dendritic cells are primed by inhaled particulate antigens, and retain MHC class II/antigenic peptide complexes in hilar lymph nodes for a prolonged period of time

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Uptake of poly(D,L-lactic-co-glycolic acid) microspheres by antigen-presenting cells in vivo

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Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro

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7 January 2021

Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2).

1 reference

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7 January 2021

N-trimethyl chitosan chloride: optimum degree of quaternization for drug absorption enhancement across epithelial cells

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7 January 2021

Evaluation of the mucoadhesive properties of N-trimethyl chitosan chloride

1 reference

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Bronchus- and nasal-associated lymphoid tissues

1 reference

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Dose response of A/Alaska/6/77 (H3N2) cold-adapted reassortant vaccine virus in adult volunteers: role of local antibody in resistance to infection with vaccine virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.06.086

7 January 2021

based on heuristic

inferred from DOI database lookup

Reactogenicity, immunogenicity, and antibody persistence in adults given inactivated influenza virus vaccines - 1978.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.06.086

7 January 2021

based on heuristic

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Identifiers

10.1016/J.VACCINE.2006.06.086

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16973248%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16973248%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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