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Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes
scientific article published on 19 September 2004
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
title
Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
main subject
type-1 diabetes
1 reference
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inferred from title
author
Harald von Boehmer
series ordinal
3
object named as
Harald von Boehmer
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
author name string
Elmar Jaeckel
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
Myra A Lipes
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
publication date
19 September 2004
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
published in
Nature Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
volume
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
issue
10
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
page(s)
1028-1035
1 reference
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Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
cites work
Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase
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7 January 2021
based on heuristic
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Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.
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Crossref
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7 January 2021
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Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
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Crossref
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7 January 2021
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Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-specific tolerance in diabetes
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
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Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment
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Crossref
reference URL
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7 January 2021
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Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes
1 reference
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Crossref
reference URL
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7 January 2021
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Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies
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7 January 2021
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inferred from DOI database lookup
International Workshop on Lessons From Animal Models for Human Type 1 Diabetes: identification of insulin but not glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
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Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
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Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
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DNA immunization to prevent autoimmune diabetes
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type I diabetes in NOD mice is not associated with insulin-specific, autoreactive T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell response to preproinsulin I and II in the nonobese diabetic mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of preproinsulin-2 gene shapes the immune response to preproinsulin in normal mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the spontaneous T cell response to insulin in NOD mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Plasmid vaccination with insulin B chain prevents autoimmune diabetes in nonobese diabetic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
Origin of regulatory T cells with known specificity for antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of insulin in relatives of patients with type 1 diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Projection of an immunological self shadow within the thymus by the aire protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo instruction of suppressor commitment in naive T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
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7 January 2021
based on heuristic
inferred from DOI database lookup
A cassette vector for high-level reporter expression driven by a hybrid invariant chain promoter in transgenic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Renaturation of human proinsulin--a study on refolding and conversion to insulin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1120
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NI1120
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
PubMed publication ID
15378058
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15378058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15378058%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
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