(Q80827612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

Christine M Eischen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Jodi R Alt

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Peng Wang

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

publication date

1 November 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

issue

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

page(s)

8931-8940

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467748%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208052

3 January 2020

exact match

0 references

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7 January 2021

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Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

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7 January 2021

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7 January 2021

Loss of p19ARF enhances the defects of Mdm2 overexpression in the mammary gland

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7 January 2021

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

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7 January 2021

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7 January 2021

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7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

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7 January 2021

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7 January 2021

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

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7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

ARF function does not require p53 stabilization or Mdm2 relocalization

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7 January 2021

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

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7 January 2021

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

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7 January 2021

mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Mdm2 regulates p53 independently of p19(ARF) in homeostatic tissues

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7 January 2021

The mdm-2 gene is induced in response to UV light in a p53-dependent manner

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7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

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7 January 2021

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7 January 2021

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7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

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7 January 2021

p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

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7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

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7 January 2021