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Loss of p19ARF enhances the defects of Mdm2 overexpression in the mammary gland
scientific article published on 01 May 2002
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
title
Loss of p19ARF enhances the defects of Mdm2 overexpression in the mammary gland
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
author name string
Carolyn J Foster
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Guillermina Lozano
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
language of work or name
English
0 references
publication date
1 May 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
21
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
22
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
3525-3531
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
cites work
A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping of the p53 and mdm-2 Interaction Domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E1A signaling to p53 involves the p19(ARF) tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An alternatively spliced HDM2 product increases p53 activity by inhibiting HDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 association with p53 targets its ubiquitination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mdm2 gene alterations and mdm2 protein expression in breast carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein status.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Geminin, an inhibitor of DNA replication, is degraded during mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm-2: "big brother" of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2 gene amplification in bone and soft‐tissue tumors: Association with tumor progression in differentiated adipose‐tissue tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of a gene encoding a p53-associated protein in human sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p16INK4a/CDKN2A tumor suppressor and its relatives.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the INK4a locus in tumor suppression and cell mortality.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between the retinoblastoma protein and the oncoprotein MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205441
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1205441
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Dimensions Publication ID
1024327975
0 references
PubMed publication ID
12032854
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12032854
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032854%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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