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English
P-TEFb inhibitors interfere with activation of p53 by DNA-damaging agents
scientific article published on 03 September 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
title
P-TEFb inhibitors interfere with activation of p53 by DNA-damaging agents
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
author
Senthil K Radhakrishnan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
author name string
Bhat UG
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
Halasi M
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
Gartel AL
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
publication date
3 September 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
volume
27
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
issue
9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
page(s)
1306-1309
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1210737
0 references
cites work
Regulation of p53 function and stability by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase 1 trial of flavopiridol combined with cisplatin or carboplatin in patients with advanced malignancies with the assessment of pharmacokinetic and pharmacodynamic end points.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flavopiridol induces p53 via initial inhibition of Mdm2 and p21 and, independently of p53, sensitizes apoptosis-reluctant cells to tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance of p53 knockout cells to doxorubicin is related to reduced formation of DNA strand breaks rather than impaired apoptotic signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21(WAF1/CIP1) response to genotoxic agents in wild-type TP53 expressing breast primary tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase and checkpoint kinase 2 synergistically activate a latent population of p53 upon DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK9 phosphorylates p53 on serine residues 33, 315 and 392
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Surfing the p53 network
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ins and outs of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase acts upstream of p53 in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210737
retrieved
7 January 2021
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Identifiers
DOI
10.1038/SJ.ONC.1210737
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
Dimensions Publication ID
1031359654
0 references
PubMed publication ID
17724473
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17724473
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724473%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 January 2020
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