(Q81086826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413240%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

In vitro assays to characterize inhibitors of the activation of small G proteins by their guanine nucleotide exchange factors (English)

1 reference

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5 January 2020

2

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5 January 2020

author name string

Jean-Christophe Zeeh

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413240%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Jacqueline Cherfils

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413240%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Mahel Zeghouf

series ordinal

4

1 reference

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5 January 2020

publication date

1 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413240%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

published in

Methods in Enzymology

1 reference

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5 January 2020

volume

438

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413240%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

page(s)

41-56

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Bacterial cytotoxins: targeting eukaryotic switches

5 January 2020

cites work

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7 January 2021

Structure of the human ADP-ribosylation factor 1 complexed with GDP

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7 January 2021

A glutamic finger in the guanine nucleotide exchange factor ARNO displaces Mg2+ and the beta-phosphate to destabilize GDP on ARF1.

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7 January 2021

Identification of TRIO-GEFD1 chemical inhibitors using the yeast exchange assay

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7 January 2021

A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains

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7 January 2021

GEFs: structural basis for their activation of small GTP-binding proteins

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7 January 2021

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

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7 January 2021

Vps9, Rabex-5 and DSS4: proteins with weak but distinct nucleotide-exchange activities for Rab proteins

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7 January 2021

A detergent-based assay for the detection of promiscuous inhibitors

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7 January 2021

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

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7 January 2021

Structural Basis for Activation of ARF GTPase

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7 January 2021

Probing the physical basis for trp repressor-operator recognition

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7 January 2021

Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance

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7 January 2021

S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells.

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7 January 2021

Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

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7 January 2021

Fluorescence approaches for monitoring interactions of Rho GTPases with nucleotides, regulators, and effectors.

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7 January 2021

Fluorescence approaches to study of protein-nucleic acid complexation

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7 January 2021

Mechanism of nucleotide release from Rho by the GDP dissociation stimulator protein

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7 January 2021

Brefeldin A revealing the fundamental principles governing membrane dynamics and protein transport.

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7 January 2021

Kinetics of interaction of nucleotides with nucleotide-free H-ras p21

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7 January 2021

The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

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7 January 2021

Targeting Rho in cardiovascular disease

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7 January 2021

Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm

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7 January 2021

Analysis of intrinsic and CDC25-stimulated guanine nucleotide exchange of p21ras-nucleotide complexes by fluorescence measurements

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7 January 2021

Controlling small guanine-nucleotide-exchange factor function through cytoplasmic RNA intramers

1 reference

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7 January 2021

Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism

1 reference

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7 January 2021

A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes

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7 January 2021

Structure-function based design of small molecule inhibitors targeting Rho family GTPases

1 reference

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7 January 2021

Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain

1 reference

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7 January 2021

Nucleotide exchange on ARF mediated by yeast Gea1 protein.

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7 January 2021

Rho proteins, mental retardation and the cellular basis of cognition

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7 January 2021

Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor

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7 January 2021

Germline gain-of-function mutations in SOS1 cause Noonan syndrome

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7 January 2021

Binding site of brefeldin A at the interface between the small G protein ADP-ribosylation factor 1 (ARF1) and the nucleotide-exchange factor Sec7 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2938004-X

7 January 2021

Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases

1 reference

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7 January 2021

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

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7 January 2021

Numerical analysis of binding data: advantages, practical aspects, and implications

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7 January 2021

RHO-GTPases and cancer

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7 January 2021

Identification of the first Rho-GEF inhibitor, TRIPalpha, which targets the RhoA-specific GEF domain of Trio

1 reference

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7 January 2021

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex

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7 January 2021

Decumbin, a New Compound from a Species of Penicillium

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7 January 2021

Antiviral activity of brefeldin A and verrucarin A.

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7 January 2021

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

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7 January 2021

Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes

1 reference

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7 January 2021

A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1.

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7 January 2021

Ras-A Molecular Switch Involved in Tumor Formation

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7 January 2021

Dual specificity of the interfacial inhibitor brefeldin a for arf proteins and sec7 domains

1 reference

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7 January 2021

Arf, Sec7 and Brefeldin A: a model towards the therapeutic inhibition of guanine nucleotide-exchange factors

1 reference

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7 January 2021

10.1016/S0076-6879(07)38004-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413240%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference