(Q81367931)

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Conformational constraints imposed on a pan-neutralizing HIV-1 antibody epitope result in increased antigenicity but not neutralizing response

scientific article published on 01 February 2005

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8 January 2020

Conformational constraints imposed on a pan-neutralizing HIV-1 antibody epitope result in increased antigenicity but not neutralizing response (English)

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8 January 2020

author name string

Jason Ho

1

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8 January 2020

Robert A Uger

2

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8 January 2020

Michael B Zwick

3

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8 January 2020

Mark A Luscher

4

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8 January 2020

Brian H Barber

5

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8 January 2020

Kelly S MacDonald

6

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8 January 2020

publication date

1 February 2005

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8 January 2020

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15

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8 January 2020

23

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13

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8 January 2020

1559-1573

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8 January 2020

Viral evolution and challenges in the development of HIV vaccines

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

1 reference

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7 January 2021

Neutralizing antibodies against HIV -- back in the major leagues?

1 reference

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7 January 2021

Structure-affinity relationships in the gp41 ELDKWA epitope for the HIV-1 neutralizing monoclonal antibody 2F5: effects of side-chain and backbone modifications and conformational constraints

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Fine definition of the epitope on the gp41 glycoprotein of human immunodeficiency virus type 1 for the neutralizing monoclonal antibody 2F5.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Immunogenic presentation of a conserved gp41 epitope of human immunodeficiency virus type 1 on recombinant surface antigen of hepatitis B virus.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Epitope insertion into variable loops of HIV-1 gp120 as a potential means to improve immunogenicity of viral envelope protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Enhancement of alpha -helicity in the HIV-1 inhibitory peptide DP178 leads to an increased affinity for human monoclonal antibody 2F5 but does not elicit neutralizing responses in vitro. Implications for vaccine design

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

HIV-1 vaccine development: constrained peptide immunogens show improved binding to the anti-HIV-1 gp41 MAb

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Construction of recombinant targeting immunogens incorporating an HIV-1 neutralizing epitope into sites of differing conformational constraint

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

The immunotargeting approach to adjuvant-independent subunit vaccine design

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Cross-Neutralizing Human Monoclonal Anti-HIV-1 Antibody 2F5: Preparation and Crystallographic Analysis of the Free and Epitope-Complexed Forms of its F ab Fragment

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

A monoclonal antibody specific for mouse dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Cross-reaction of a monoclonal antibody to human MHC class II molecules with rabbit B cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Antigenicity and immunogenicity of synthetic peptides

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Molecular Characterization of Five Neutralizing Anti-HIV Type 1 Antibodies: Identification of Nonconventional D Segments in the Human Monoclonal Antibodies 2G12 and 2F5

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Anti-idiotypic antibody Ab2/3H6 mimics the epitope of the neutralizing anti-HIV-1 monoclonal antibody 2F5

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.09.037

7 January 2021

Identifiers

10.1016/J.VACCINE.2004.09.037

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15694508%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

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8 January 2020

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