(Q81446954)

8 January 2020

review article

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title

TAZ encodes tafazzin, a transacylase essential for cardiolipin formation and central to the etiology of Barth syndrome. (English)

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8 January 2020

part of the series

Gene Wiki Review Series

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author name string

Anders O Garlid

1

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8 January 2020

Calvin T Schaffer

2

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8 January 2020

Jaewoo Kim

3

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8 January 2020

Hirsh Bhatt

4

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8 January 2020

Vladimir Guevara-Gonzalez

5

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8 January 2020

Peipei Ping

6

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8 January 2020

publication date

21 October 2019

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8 January 2020

published in

Gene

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8 January 2020

volume

726

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8 January 2020

page(s)

144148

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8 January 2020

X-linked dilated cardiomyopathy with neutropenia, growth retardation, and 3-methylglutaconic aciduria

cites work

1 reference

12 December 2020

A canine model of chronic heart failure produced by multiple sequential coronary microembolizations

1 reference

12 December 2020

Dilated cardiomyopathy with neutropenia, short stature, and abnormal carnitine metabolism

1 reference

12 December 2020

Two cases of endocardial fibroelastosis--possible x-linked determination

1 reference

12 December 2020

An X-linked mitochondrial disease affecting cardiac muscle, skeletal muscle and neutrophil leucocytes

1 reference

12 December 2020

Barth syndrome: clinical observations and genetic linkage studies.

1 reference

12 December 2020

Transcriptional organization of a 450-kb region of the human X chromosome in Xq28

1 reference

12 December 2020

Barth syndrome: clinical features and confirmation of gene localisation to distal Xq28.

1 reference

12 December 2020

A novel X-linked gene, G4.5. is responsible for Barth syndrome

1 reference

12 December 2020

X-linked cardioskeletal myopathy and neutropenia (Barth syndrome): respiratory-chain abnormalities in cultured fibroblasts

1 reference

12 December 2020

Heart transplantation for Barth syndrome

1 reference

12 December 2020

Barth syndrome may be due to an acyltransferase deficiency

1 reference

12 December 2020

Xq28-linked noncompaction of the left ventricular myocardium: prenatal diagnosis and pathologic analysis of affected individuals

1 reference

12 December 2020

Prenatal clinical expression of 3-methylglutaconic aciduria: Barth syndrome

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12 December 2020

A conserved histidine is essential for glycerolipid acyltransferase catalysis

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12 December 2020

Import of lipids into mitochondria

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12 December 2020

Genetic analysis of the G4.5 gene in families with suspected Barth syndrome

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12 December 2020

Supercomplexes in the respiratory chains of yeast and mammalian mitochondria

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12 December 2020

Opening mitochondrial K(ATP) in the heart--what happens, and what does not happen

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12 December 2020

Cardioprotection by ischemic preconditioning preserves mitochondrial function and functional coupling between adenine nucleotide translocase and creatine kinase.

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12 December 2020

Non-Epstein-Barr virus-associated T-cell lymphoma following cardiac transplantation for Barth syndrome

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12 December 2020

Respiratory chain supercomplexes

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12 December 2020

Normal pituitary function in a Japanese patient with Barth syndrome

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12 December 2020

Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage

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12 December 2020

Novel missense mutation (R94S) in the TAZ ( G4.5) gene in a Japanese patient with Barth syndrome.

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12 December 2020

Cardiolipin: a proton trap for oxidative phosphorylation.

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12 December 2020

Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane

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12 December 2020

Cardiolipin deficiency in X-linked cardioskeletal myopathy and neutropenia (Barth syndrome, MIM 302060): a study in cultured skin fibroblasts

1 reference

12 December 2020

A novel mutation in the G4.5 (TAZ) gene in a kindred with Barth syndrome.

1 reference

12 December 2020

Genetic fate of recombinant adeno-associated virus vector genomes in muscle

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12 December 2020

Only one splice variant of the human TAZ gene encodes a functional protein with a role in cardiolipin metabolism

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12 December 2020

Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome.

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12 December 2020

Long-term treatment of Barth syndrome with pantothenic acid: a retrospective study

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12 December 2020

Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria

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12 December 2020

Substrate recognition and selectivity of plant glycerol-3-phosphate acyltransferases (GPATs) from Cucurbita moscata and Spinacea oleracea

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12 December 2020

X-linked cardioskeletal myopathy and neutropenia (Barth syndrome): an update

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12 December 2020

Barth syndrome without 3-methylglutaconic aciduria.

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12 December 2020

Octameric mitochondrial creatine kinase induces and stabilizes contact sites between the inner and outer membrane

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12 December 2020

The human TAZ gene complements mitochondrial dysfunction in the yeast taz1Delta mutant. Implications for Barth syndrome

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12 December 2020

Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis

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12 December 2020

Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release

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12 December 2020

Characterization of lymphoblast mitochondria from patients with Barth syndrome

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12 December 2020

Clinicopathologic conference: Barth Syndrome

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12 December 2020

Cardiac system bioenergetics: metabolic basis of the Frank-Starling law.

1 reference

12 December 2020

X-linked fetal cardiomyopathy caused by a novel mutation in the TAZ gene.

1 reference

12 December 2020

Mechanisms of cardiolipin oxidation by cytochrome c: relevance to pro- and antiapoptotic functions of etoposide

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12 December 2020

Identification and functional characterization of hCLS1, a human cardiolipin synthase localized in mitochondria

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12 December 2020

Non-compaction cardiomyopathy in an adult with hereditary spherocytosis

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12 December 2020

Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients

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12 December 2020

Mitochondrial mislocalization and altered assembly of a cluster of Barth syndrome mutant tafazzins

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12 December 2020

Stroke associated with Barth syndrome.

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12 December 2020

Comparison of lymphoblast mitochondria from normal subjects and patients with Barth syndrome using electron microscopic tomography

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12 December 2020

The enzymatic function of tafazzin

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12 December 2020

Cardiolipin Clusters and Membrane Domain Formation Induced by Mitochondrial Proteins

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12 December 2020

Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.

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12 December 2020

Multiple transmissions of Barth syndrome through an oocyte donor with a de novo TAZ mutation

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12 December 2020

Barth syndrome is associated with a cognitive phenotype

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12 December 2020

Barth syndrome associated with compound hemizygosity and heterozygosity of the TAZ and LDB3 genes.

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12 December 2020

Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure

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12 December 2020

Successful cardiac transplantation in Barth syndrome--single-centre experience of four patients

1 reference

12 December 2020

Acute metabolic decompensation and sudden death in Barth syndrome: report of a family and a literature review.

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12 December 2020

Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype

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12 December 2020

Bloodspot assay using HPLC-tandem mass spectrometry for detection of Barth syndrome

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12 December 2020

Cardiolipin synthesis for the assembly of bacterial and mitochondrial membranes

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12 December 2020

Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat

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12 December 2020

Intramitochondrial signaling: interactions among mitoKATP, PKCepsilon, ROS, and MPT

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12 December 2020

The Severe Chronic Neutropenia International Registry: 10-Year Follow-up Report

1 reference

12 December 2020

Cardiomyopathy in a child with neutropenia and motor delay.

1 reference

12 December 2020

Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat.

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12 December 2020

Supercomplex organization of the oxidative phosphorylation enzymes in yeast mitochondria

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12 December 2020

Mitral annuloplasty in an infant with Barth syndrome and severe mitral insufficiency: First case report and determination of annular diameter

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12 December 2020

Cardiomyopathy of unknown etiology: Barth syndrome unrecognized

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12 December 2020

Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome

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12 December 2020

Identification of a cardiolipin-specific phospholipase encoded by the gene CLD1 (YGR110W) in yeast

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12 December 2020

A novel mutation in the G4.5 (TAZ) gene in a Greek patient with Barth syndrome

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12 December 2020

MitoKATP activity in healthy and ischemic hearts

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12 December 2020

A novel Alu-mediated Xq28 microdeletion ablates TAZ and partially deletes DNL1L in a patient with Barth syndrome

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12 December 2020

Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis.

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12 December 2020

Cardiolipin and monolysocardiolipin analysis in fibroblasts, lymphocytes, and tissues using high-performance liquid chromatography-mass spectrometry as a diagnostic test for Barth syndrome.

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12 December 2020

The enigmatic role of tafazzin in cardiolipin metabolism

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12 December 2020

Separation and characterization of cardiolipin molecular species by reverse-phase ion pair high-performance liquid chromatography-mass spectrometry

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12 December 2020

Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB Ca2+-independent phospholipase A2gamma-deficient mice

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12 December 2020

Barth syndrome: an X-linked cause of fetal cardiomyopathy and stillbirth

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12 December 2020

The 3-methylglutaconic acidurias: what's new?

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12 December 2020

Barth syndrome: an X-linked cardiomyopathy with a novel mutation

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12 December 2020

Caspase-8 and bid: caught in the act between death receptors and mitochondria

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12 December 2020

Cardiolipin microdomains localize to negatively curved regions of Escherichia coli membranes

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12 December 2020

Revisiting gap locations in amino acid sequence alignments and a proposal for a method to improve them by introducing solvent accessibility

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12 December 2020

Cardiolipin affects the supramolecular organization of ATP synthase in mitochondria

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12 December 2020

Impaired cardiac reserve and severely diminished skeletal muscle O₂ utilization mediate exercise intolerance in Barth syndrome.

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12 December 2020

Barth syndrome diagnosed in the subclinical stage of heart failure based on the presence of lipid storage myopathy and isolated noncompaction of the ventricular myocardium

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12 December 2020

Differing clinical courses and outcomes in two siblings with Barth syndrome and left ventricular noncompaction

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12 December 2020

The cellular and molecular mechanisms for neutropenia in Barth syndrome

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12 December 2020

Barth syndrome in a female patient

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12 December 2020

Molecular basis of the interaction between proapoptotic truncated BID (tBID) protein and mitochondrial carrier homologue 2 (MTCH2) protein: key players in mitochondrial death pathway

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12 December 2020

Left ventricular noncompaction cardiomyopathy in Barth syndrome: an example of an undulating cardiac phenotype necessitating mechanical circulatory support as a bridge to transplantation

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12 December 2020

Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study

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12 December 2020

Metabolic labeling reveals proteome dynamics of mouse mitochondria

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12 December 2020

The physical state of lipid substrates provides transacylation specificity for tafazzin

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12 December 2020

Tafazzin senses curvature

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12 December 2020

Barth syndrome in adulthood: a clinical case

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12 December 2020

Intrafamilial variability for novel TAZ gene mutation: Barth syndrome with dilated cardiomyopathy and heart failure in an infant and left ventricular noncompaction in his great-uncle

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12 December 2020

The Barth Syndrome Registry: Distinguishing disease characteristics and growth data from a longitudinal study

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12 December 2020

Seven functional classes of Barth syndrome mutation

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12 December 2020

Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation

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12 December 2020

Successful mechanical circulatory support for 251 days in a child with intermittent severe neutropenia due to Barth syndrome

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12 December 2020

Cardiolipin remodeling and the function of tafazzin

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12 December 2020

Inborn errors of metabolism with 3-methylglutaconic aciduria as discriminative feature: proper classification and nomenclature

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12 December 2020

NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy

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12 December 2020

Left ventricular noncompaction (LVNC) and low mitochondrial membrane potential are specific for Barth syndrome.

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12 December 2020

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12 December 2020

New clinical and molecular insights on Barth syndrome

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12 December 2020

Advances in the understanding of Barth syndrome

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12 December 2020

Assessing phospholipase A2 activity toward cardiolipin by mass spectrometry

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12 December 2020

Emerging roles of cardiolipin remodeling in mitochondrial dysfunction associated with diabetes, obesity, and cardiovascular diseases

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12 December 2020

A Novel Exonic Splicing Mutation in the TAZ (G4.5) Gene in a Case with Atypical Barth Syndrome

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12 December 2020

Deacylation on the matrix side of the mitochondrial inner membrane regulates cardiolipin remodeling

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12 December 2020

Natural history of Barth syndrome: a national cohort study of 22 patients

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12 December 2020

A novel mutation of the TAZ gene in Barth syndrome: acute exacerbation after contrast-dye injection.

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12 December 2020

Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome

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12 December 2020

Mitochondrial membrane lipid remodeling in pathophysiology: a new target for diet and therapeutic interventions.

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12 December 2020

Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis

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12 December 2020

Mitochondrial reactive oxygen species: which ROS signals cardioprotection?

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12 December 2020

The Taz1p transacylase is imported and sorted into the outer mitochondrial membrane via a membrane anchor domain.

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12 December 2020

Novel mutations in the TAZ gene in patients with Barth syndrome

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12 December 2020

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

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12 December 2020

Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis

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12 December 2020

Cardiolipin-dependent formation of mitochondrial respiratory supercomplexes

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12 December 2020

Left ventricular noncompaction cardiomyopathy

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12 December 2020

Unremodeled and remodeled cardiolipin are functionally indistinguishable in yeast

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12 December 2020

Metabolic biology of 3-methylglutaconic acid-uria: a new perspective

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12 December 2020

Clinical laboratory studies in Barth Syndrome.

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12 December 2020

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

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12 December 2020

Membrane curvature modulation of protein activity determined by NMR.

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12 December 2020

Cardiomyopathy in a male patient with neutropenia and growth delay

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12 December 2020

Barth syndrome without tetralinoleoyl cardiolipin deficiency: a possible ameliorated phenotype

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12 December 2020

Mitochondria-targeted antioxidant prevents cardiac dysfunction induced by tafazzin gene knockdown in cardiac myocytes

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12 December 2020

Scavenging of H2O2 by mouse brain mitochondria.

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12 December 2020

Cardiolipin remodeling: a regulatory hub for modulating cardiolipin metabolism and function

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12 December 2020

Role of mitochondrial lipids in guiding fission and fusion

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12 December 2020

Tafazzins from Drosophila and mammalian cells assemble in large protein complexes with a short half-life.

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12 December 2020

A novel TAZ gene mutation and mosaicism in a Polish family with Barth syndrome

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12 December 2020

Intra-individual plasticity of the TAZ gene leading to different heritable mutations in siblings with Barth syndrome

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12 December 2020

Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy

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12 December 2020

Structural and functional analyses of Barth syndrome-causing mutations and alternative splicing in the tafazzin acyltransferase domain.

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12 December 2020

Exogenous cardiolipin localizes to mitochondria and prevents TAZ knockdown-induced apoptosis in myeloid progenitor cells

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12 December 2020

Successful management of Barth syndrome: a systematic review highlighting the importance of a flexible and multidisciplinary approach

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12 December 2020

Atypical Clinical Presentations of TAZ Mutations: An Underdiagnosed Cause of Growth Retardation?

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12 December 2020

Bezafibrate for the treatment of dyslipidemia in patients with coronary artery disease: 20-year mortality follow-up of the BIP randomized control trial

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12 December 2020

Barth Syndrome: From Mitochondrial Dysfunctions Associated with Aberrant Production of Reactive Oxygen Species to Pluripotent Stem Cell Studies

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12 December 2020

Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure

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12 December 2020

New targets for monitoring and therapy in Barth syndrome

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12 December 2020

When silence is noise: infantile-onset Barth syndrome caused by a synonymous substitution affecting TAZ gene transcription.

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12 December 2020

Prospective and Retrospective Diagnosis of Barth Syndrome Aided by Next-Generation Sequencing.

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12 December 2020

Mechanism for Remodeling of the Acyl Chain Composition of Cardiolipin Catalyzed by Saccharomyces cerevisiae Tafazzin

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12 December 2020

Identification of a Novel De Novo Mutation of the TAZ Gene in a Korean Patient with Barth Syndrome

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12 December 2020

Cardiolipin puts the seal on ATP synthase

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12 December 2020

The architecture of the mammalian respirasome

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12 December 2020

Genetic bases of dilated cardiomyopathy.

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12 December 2020

Barth Syndrome: Connecting Cardiolipin to Cardiomyopathy

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12 December 2020

Barth Syndrome with Late-Onset Cardiomyopathy: A Missed Opportunity for Diagnosis

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12 December 2020

A novel mutation in TAZ causes mitochondrial respiratory chain disorder without cardiomyopathy.

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12 December 2020

Identification of TAZ mutations in pediatric patients with cardiomyopathy by targeted next-generation sequencing in a Chinese cohort.

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12 December 2020

The Basis for Acyl Specificity in the Tafazzin Reaction

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12 December 2020

Neonatal dilated cardiomyopathy

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12 December 2020

The PPAR pan-agonist bezafibrate ameliorates cardiomyopathy in a mouse model of Barth syndrome

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12 December 2020

Pediatric Heart Failure: A Practical Guide to Diagnosis and Management

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12 December 2020

A novel intronic splice site tafazzin gene mutation detected prenatally in a family with Barth syndrome

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12 December 2020

Soft Matter in Lipid-Protein Interactions

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12 December 2020

Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin.

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12 December 2020

Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy

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12 December 2020

Identification of novel mitochondrial localization signals in human Tafazzin, the cause of the inherited cardiomyopathic disorder Barth syndrome

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12 December 2020

Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide.

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12 December 2020

Barth Syndrome: Different Approaches to Diagnosis.

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12 December 2020

Evaluation of cardiolipin nanodisks as lipidreplacement therapy for Barth syndrome.

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12 December 2020

Expression of human monolysocardiolipin acyltransferase-1 improves mitochondrial function in Barth Syndrome lymphoblasts.

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12 December 2020

Molecular structural diversity of mitochondrial cardiolipins.

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12 December 2020

SWISS-MODEL: homology modelling of protein structures and complexes.

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12 December 2020

Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome

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12 December 2020

Aberrant cardiolipin metabolism is associated with cognitive deficiency and hippocampal alteration in tafazzin knockdown mice

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12 December 2020

AAV-Mediated TAZ Gene Replacement Restores Mitochondrial and Cardioskeletal Function in Barth Syndrome

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12 December 2020

Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin

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12 December 2020

Neutropenia in Barth syndrome: characteristics, risks, and management

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12 December 2020

A reference set of curated biomedical data and metadata from clinical case reports

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12 December 2020

Effects of elamipretide on skeletal muscle in dogs with experimentally induced heart failure

1 reference

12 December 2020

AAV9-TAZ Gene Replacement Ameliorates Cardiac TMT Proteomic Profiles in a Mouse Model of Barth Syndrome

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12 December 2020

Elamipretide Improves Mitochondrial Function in the Failing Human Heart

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12 December 2020

Assembly of the complexes of oxidative phosphorylation triggers the remodeling of cardiolipin

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12 December 2020

10.1016/J.GENE.2019.144148

Identifiers

DOI

1 reference

8 January 2020

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1 reference

8 January 2020