(Q82418956)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20054175%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

A heterozygous mutation in the third transmembrane domain causes a dominant-negative effect on signalling capability of the MC4R (English)

1 reference

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16 January 2020

1 reference

Patrick Tarnow

1

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16 January 2020

Anne Rediger

2

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16 January 2020

Harald Brumm

3

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16 January 2020

Petra Ambrugger

4

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16 January 2020

Eva Rettenbacher

5

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16 January 2020

Kurt Widhalm

6

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16 January 2020

Anke Hinney

7

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16 January 2020

Gunnar Kleinau

8

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16 January 2020

Michael Schaefer

9

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16 January 2020

Johannes Hebebrand

10

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16 January 2020

Gerd Krause

11

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16 January 2020

Annette Grüters

12

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16 January 2020

Heike Biebermann

13

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16 January 2020

publication date

20 June 2008

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16 January 2020

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16 January 2020

volume

1

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16 January 2020

issue

3

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16 January 2020

page(s)

155-162

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Identification and functional analysis of novel human melanocortin-4 receptor variants

16 January 2020

cites work

1 reference

12 December 2020

Functional characterization of mutations in melanocortin-4 receptor associated with human obesity

1 reference

12 December 2020

Structural implication for receptor oligomerization from functional reconstitution studies of mutant V2 vasopressin receptors.

1 reference

12 December 2020

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

12 December 2020

Oligomerization of G-protein-coupled transmitter receptors.

1 reference

12 December 2020

Partial leptin deficiency and human adiposity.

1 reference

12 December 2020

G-protein-coupled receptor oligomerization and its potential for drug discovery

1 reference

12 December 2020

Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma

1 reference

12 December 2020

Structural models for dimerization of G-protein coupled receptors: the opioid receptor homodimers.

1 reference

12 December 2020

Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms

1 reference

12 December 2020

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

1 reference

12 December 2020

β-MSH: a functional ligand that regulated energy homeostasis via hypothalamic MC4-R?

1 reference

12 December 2020

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

1 reference

12 December 2020

Mutationally Induced Disulfide Bond Formation within the Third Extracellular Loop Causes Melanocortin 4 Receptor Inactivation in Patients with Obesity

1 reference

12 December 2020

Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

1 reference

12 December 2020

Autosomal-dominant mode of inheritance of a melanocortin-4 receptor mutation in a patient with severe early-onset obesity is due to a dominant-negative effect caused by receptor dimerization.

1 reference

12 December 2020

Identification of amino acid residues crucial for chemokine receptor dimerization.

1 reference

12 December 2020

Principles: receptor theory in pharmacology

1 reference

12 December 2020

Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index

1 reference

12 December 2020

Mutant G-protein-coupled receptors as a cause of human diseases

1 reference

12 December 2020

An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor

1 reference

12 December 2020

Anatomy and regulation of the central melanocortin system

1 reference

12 December 2020

MC4R oligomerizes independently of extracellular cysteine residues

1 reference

12 December 2020

A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance

1 reference

12 December 2020

A role for beta-melanocyte-stimulating hormone in human body-weight regulation

1 reference

12 December 2020

Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany

1 reference

12 December 2020

Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes

1 reference

12 December 2020

Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

1 reference

12 December 2020

A novel non-synonymous mutation in the melanocortin-4 receptor gene (MC4R) in a 2-year-old Austrian girl with extreme obesity

1 reference

12 December 2020

Evolutionary aspects in evaluating mutations in the melanocortin 4 receptor

1 reference

12 December 2020

Crystal Structure of a Thermally Stable Rhodopsin Mutant

1 reference

12 December 2020

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

1 reference

12 December 2020

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

12 December 2020

Molecular cloning, expression, and gene localization of a fourth melanocortin receptor

1 reference

12 December 2020

Main-chain bond lengths and bond angles in protein structures

1 reference

12 December 2020

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

1 reference

12 December 2020

Mutations of the human thyrotropin receptor gene causing thyroid hypoplasia and persistent congenital hypothyroidism

1 reference

12 December 2020

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

1 reference

12 December 2020

A frameshift mutation in MC4R associated with dominantly inherited human obesity

1 reference

12 December 2020

A frameshift mutation in human MC4R is associated with a dominant form of obesity

1 reference

12 December 2020

Identifiers

DOI

10.1159/000138251

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20054175%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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16 January 2020

PubMed publication ID

20054175

1 reference