(Q82496617)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21086121%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Frequent loss of heterozygosity in the β2-microglobulin region of chromosome 15 in primary human tumors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21086121%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

7

Federico Garrido

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21086121%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Isabel Maleno

1

1 reference

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16 January 2020

Natalia Aptsiauri

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21086121%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Teresa Cabrera

3

1 reference

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16 January 2020

Aurelia Gallego

4

1 reference

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16 January 2020

Annette Paschen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21086121%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Miguel Angel López-Nevot

6

1 reference

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16 January 2020

publication date

18 November 2010

1 reference

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16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21086121%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

63

1 reference

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16 January 2020

issue

2

1 reference

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16 January 2020

page(s)

65-71

1 reference

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https://scigraph.springernature.com/pub.10.1007/s00251-010-0494-4

16 January 2020

exact match

0 references

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Human epithelial ovarian cancer allelotype.

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MHC antigens and tumor escape from immune surveillance

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"Hard" and "soft" lesions underlying the HLA class I alterations in cancer cells: implications for immunotherapy

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Distribution of HLA class I altered phenotypes in colorectal carcinomas: high frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21.

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HLA class I expression in metastatic melanoma correlates with tumor development during autologous vaccination.

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Role of altered expression of HLA class I molecules in cancer progression.

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Mutations of the beta2-microglobulin gene result in a lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides

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Tumour immunology, vaccination and escape strategies

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12 December 2020

Molecular mechanisms of oncogenesis

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12 December 2020

Low frequency of HLA haplotype loss associated with loss of heterozygocity in chromosome region 6p21 in clear renal cell carcinomas

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12 December 2020

Analysis of HLA class I expression in progressing and regressing metastatic melanoma lesions after immunotherapy

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12 December 2020

HLA class I antigen down-regulation in primary laryngeal squamous cell carcinoma lesions as a poor prognostic marker.

1 reference

12 December 2020

Complete loss of HLA class I antigen expression on melanoma cells: a result of successive mutational events.

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12 December 2020

High level of chromosome 15 aneuploidy in head and neck squamous cell carcinoma lesions identified by FISH analysis: limited value of beta2-microglobulin LOH analysis

1 reference

12 December 2020

Implications for immunosurveillance of altered HLA class I phenotypes in human tumours

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12 December 2020

Human leukocyte antigen class I antigen expression is an independent prognostic factor in ovarian cancer

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12 December 2020

Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: β2‐microglobulin inactivation in MSI‐positive tumors and LMP7/TAP2 downregulation in MSI‐negative tumors

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12 December 2020

Natural history of HLA expression during tumour development.

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12 December 2020

HLA class I expression in bladder carcinomas

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12 December 2020

HLA class I expression and chromosomal deletions at 6p and 15q in head and neck squamous cell carcinomas

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12 December 2020

Loss of heterozygosity analysis defines a 3-cM region of 15q commonly deleted in human malignant mesothelioma

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12 December 2020

Multiple mechanisms generate HLA class I altered phenotypes in laryngeal carcinomas: high frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21

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12 December 2020

A distinct tumor suppressor gene locus on chromosome 15q21.1 in sporadic form of colorectal cancer.

1 reference

12 December 2020

High-resolution deletion mapping of 15q13.2-q21.1 in transitional cell carcinoma of the bladder

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12 December 2020

Loss of heterozygosity at 15q21.3 correlates with occurrence of metastases in head and neck cancer.

1 reference

12 December 2020

Immune selection of hot-spot beta 2-microglobulin gene mutations, HLA-A2 allospecificity loss, and antigen-processing machinery component down-regulation in melanoma cells derived from recurrent metastases following immunotherapy

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12 December 2020

LOH at 6p21.3 region and HLA class I altered phenotypes in bladder carcinomas

1 reference

12 December 2020

Chromosomal region 15q21.1 is a frequent target of allelic imbalance in advanced breast carcinomas

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12 December 2020

Impaired surface antigen presentation in tumors: implications for T cell-based immunotherapy.

1 reference

12 December 2020

Identification of different tumor escape mechanisms in several metastases from a melanoma patient undergoing immunotherapy

1 reference

12 December 2020

beta(2)microglobulin mRNA expression levels are prognostic for lymph node metastasis in colorectal cancer patients

1 reference

12 December 2020

Coordinated downregulation of the antigen presentation machinery and HLA class I/beta2-microglobulin complex is responsible for HLA-ABC loss in bladder cancer

1 reference

12 December 2020

Molecular strategies to define HLA haplotype loss in microdissected tumor cells

1 reference

12 December 2020

Regressing and progressing metastatic lesions: resistance to immunotherapy is predetermined by irreversible HLA class I antigen alterations

1 reference

12 December 2020

Efficient recovery of HLA class I expression in human tumor cells after beta2-microglobulin gene transfer using adenoviral vector: implications for cancer immunotherapy

1 reference

12 December 2020

Antigen-processing machinery breakdown and tumor growth

1 reference

12 December 2020

The coincidence of chromosome 15 aberrations and beta2-microglobulin gene mutations is causative for the total loss of human leukocyte antigen class I expression in melanoma

1 reference

12 December 2020