(Q82526832)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22087866%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

meta-analysis

0 references

title

Population pharmacokinetic meta-analysis of denosumab in healthy subjects and postmenopausal women with osteopenia or osteoporosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22087866%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Liviawati Sutjandra

1

1 reference

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16 January 2020

Rachelle D Rodriguez

2

1 reference

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16 January 2020

Sameer Doshi

3

1 reference

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16 January 2020

Mark Ma

4

1 reference

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16 January 2020

Mark C Peterson

5

1 reference

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16 January 2020

Graham R Jang

6

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16 January 2020

Andrew T Chow

7

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16 January 2020

Juan José Pérez-Ruixo

8

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16 January 2020

publication date

1 December 2011

1 reference

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Clinical Pharmacokinetics

16 January 2020

published in

1 reference

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16 January 2020

volume

50

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16 January 2020

issue

12

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16 January 2020

page(s)

793-807

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Likelihood based approaches to handling data below the quantification limit using NONMEM VI.

16 January 2020

cites work

1 reference

12 December 2020

Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines

1 reference

12 December 2020

Osteoprotegerin and RANKL regulate bone resorption, density, geometry and strength

1 reference

12 December 2020

Antibody pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

General pharmacokinetic model for drugs exhibiting target-mediated drug disposition

1 reference

12 December 2020

Effect of denosumab on bone density and turnover in postmenopausal women with low bone mass after long-term continued, discontinued, and restarting of therapy: a randomized blinded phase 2 clinical trial

1 reference

12 December 2020

Population pharmacokinetics of clinafloxacin in healthy volunteers and patients with infections: experience with heterogeneous pharmacokinetic data

1 reference

12 December 2020

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

1 reference

12 December 2020

Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions

1 reference

12 December 2020

Osteoclastogenesis inhibitory factor suppresses osteoclast survival by interfering in the interaction of stromal cells with osteoclast

1 reference

12 December 2020

The effect of a single dose of osteoprotegerin in postmenopausal women

1 reference

12 December 2020

The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.

1 reference

12 December 2020

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1 reference

12 December 2020

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

1 reference

12 December 2020

Population Pharmacokinetics of Therapeutic Monoclonal Antibodies

1 reference

12 December 2020

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

1 reference

12 December 2020

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1 reference

12 December 2020

Effects of denosumab on bone mineral density and bone turnover in postmenopausal women

1 reference

12 December 2020

Selection between Michaelis-Menten and target-mediated drug disposition pharmacokinetic models

1 reference

12 December 2020

Nonlinear pharmacokinetics of therapeutic proteins resulting from receptor mediated endocytosis

1 reference

12 December 2020

Integrated cellular bone homeostasis model for denosumab pharmacodynamics in multiple myeloma patients

1 reference

12 December 2020

Circulating RANKL is inversely related to RANKL mRNA levels in bone in osteoarthritic males.

1 reference

12 December 2020

Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL.

1 reference

12 December 2020

Osteoprotegerin: a physiological and pharmacological inhibitor of bone resorption

1 reference

12 December 2020

Denosumab in men receiving androgen-deprivation therapy for prostate cancer

1 reference

12 December 2020

Impact of censoring data below an arbitrary quantification limit on structural model misspecification

1 reference

12 December 2020

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women

1 reference

12 December 2020

Target-mediated drug disposition model: approximations, identifiability of model parameters and applications to the population pharmacokinetic-pharmacodynamic modeling of biologics

1 reference

12 December 2020

Effects of oral contraceptives on circulating osteoprotegerin and soluble RANK ligand serum levels in healthy young women

1 reference

12 December 2020

Evaluating pharmacokinetic/pharmacodynamic models using the posterior predictive check

1 reference

12 December 2020

The role of mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modelling in translational research of biologics

1 reference

12 December 2020

Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition.

1 reference

12 December 2020

Handling data below the limit of quantification in mixed effect models

1 reference

12 December 2020

Denosumab in postmenopausal women with low bone mineral density

1 reference

12 December 2020

A mechanism-based binding model for the population pharmacokinetics and pharmacodynamics of omalizumab.

1 reference

12 December 2020

Denosumab for prevention of fractures in postmenopausal women with osteoporosis

1 reference

12 December 2020

Ways to fit a PK model with some data below the quantification limit

1 reference

12 December 2020

Relationships between the changes of serum levels of OPG and RANKL with age, menopause, bone biochemical markers and bone mineral density in Chinese women aged 20-75

1 reference

12 December 2020

Approximations of the target-mediated drug disposition model and identifiability of model parameters.

1 reference

12 December 2020

Population pharmacokinetics meta-analysis of recombinant human erythropoietin in healthy subjects.

1 reference

12 December 2020

Population pharmacokinetics of tipifarnib in healthy subjects and adult cancer patients

1 reference

12 December 2020

Monoclonal antibody pharmacokinetics and pharmacodynamics

1 reference

12 December 2020