(Q82662160)

English

Oral ingestion of Capsaicin, the pungent component of chili pepper, enhances a discreet population of macrophages and confers protection from autoimmune diabetes

scientific article published on 23 November 2011

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scholarly article

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17 January 2020

Oral ingestion of Capsaicin, the pungent component of chili pepper, enhances a discreet population of macrophages and confers protection from autoimmune diabetes (English)

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17 January 2020

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17 January 2020

author name string

P K Srivastava

2

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17 January 2020

S Basu

3

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17 January 2020

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23 November 2011

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17 January 2020

Mucosal Immunology

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17 January 2020

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17 January 2020

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17 January 2020

76-86

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17 January 2020

https://scigraph.springernature.com/pub.10.1038/mi.2011.50

0 references

The cloned capsaicin receptor integrates multiple pain-producing stimuli

1 reference

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Ion channels gated by heat

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Impaired nociception and pain sensation in mice lacking the capsaicin receptor

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Tolerogenic dendritic cells

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Mucosal dendritic cells

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Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

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Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

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Anatomical basis of tolerance and immunity to intestinal antigens

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Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patch

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Endocrine self and gut non-self intersect in the pancreatic lymph nodes

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Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry

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Delayed exposure to wheat and barley proteins reduces diabetes incidence in non-obese diabetic mice

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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

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Oral insulin for diabetes prevention in NOD mice: potentiation by enhancing Th2 cytokine expression in the gut through bacterial adjuvant

1 reference

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

1 reference

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7 January 2021

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Constitutive class I-restricted exogenous presentation of self antigens in vivo

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7 January 2021

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Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer

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Immunotherapy of NOD mice with bone marrow-derived dendritic cells

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Oral tolerance to food-induced systemic anaphylaxis mediated by the C-type lectin SIGNR1

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Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine

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Interleukin-10 and the interleukin-10 receptor

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The capsaicin receptor: a heat-activated ion channel in the pain pathway

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Vanilloid receptor (VR1) expression in vagal afferent neurons innervating the gastrointestinal tract

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Characterization of the primary spinal afferent innervation of the mouse colon using retrograde labelling

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Distribution of the vanilloid receptor (VR1) in the gastrointestinal tract

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Thermosensitive transient receptor potential channels in vagal afferent neurons of the mouse

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The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria

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Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria

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Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese-mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages

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Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice

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Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target

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Lipid mediator class switching during acute inflammation: signals in resolution.

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