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English
Dual inhibition of Jak2 and STAT5 enhances killing of myeloproliferative neoplasia cells
scientific article published on 02 December 2011
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
Dual inhibition of Jak2 and STAT5 enhances killing of myeloproliferative neoplasia cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
M Bar-Natan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
E A Nelson
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
S R Walker
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Y Kuang
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
R J Distel
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
D A Frank
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
publication date
2 December 2011
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
published in
Leukemia
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
26
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
1407-1410
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/leu.2011.338
0 references
cites work
Myeloproliferative disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic mechanisms in myeloproliferative disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F mutant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinome profiling in pediatric brain tumors as a new approach for target discovery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Janus kinases: components of multiple signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2011.338
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/LEU.2011.338
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Dimensions Publication ID
1030115403
0 references
PubMed publication ID
22134716
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22134716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22134716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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